The National Institute on Aging (NIA) Interventions Testing Program (ITP) investigates dietary supplements purported to extend lifespan and/or delay the onset of disease and disability. The NIA ITP tests such compounds in mice, using a variety of measured endpoints to assess the efficacy of interventions. The NIA ITP is not a mechanism for funding sponsors’ laboratories to perform the work, but rather it is a collaborative effort between the three NIA-funded testing sites and the sponsors who propose interventions for study. The sponsors’ role is to provide the rationale for investigating the intervention, make recommendations on the dose, route, and timing for administration of the intervention, and propose assays and measurements to document the efficacy of the intervention. The sponsor will have access to all data developed from the treated mice, will assist in analysis of the data, and will be a co-author on resulting publications. Proposals are reviewed by an Access Panel, and accepted protocols are prioritized by the ITP Steering Committee.
The NIA ITP is soliciting proposals for compounds to enter the study in 2013. The deadline for receipt of proposals is September 21, 2012.
Information on the NIA ITP and guidelines for proposal development are posted at http://www.nia.nih.gov/research/dab/interventions-testing-program-itp. Questions may be directed to Dr. Nancy Nadon (firstname.lastname@example.org).