Lnk deficiency partially mitigates hematopoietic stem cell aging
Article first published online: 27 AUG 2012
© 2012 The Authors. Aging Cell © 2012 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
Volume 11, Issue 6, pages 949–959, December 2012
How to Cite
Bersenev, A., Rozenova, K., Balcerek, J., Jiang, J., Wu, C. and Tong, W. (2012), Lnk deficiency partially mitigates hematopoietic stem cell aging. Aging Cell, 11: 949–959. doi: 10.1111/j.1474-9726.2012.00862.x
- Issue published online: 15 NOV 2012
- Article first published online: 27 AUG 2012
- Accepted manuscript online: 20 JUL 2012 01:01AM EST
- Accepted for publication 10 September 2012
Fig. S1. Lineage reconstitution of serial transplanted mice.
Fig. S2. Determination of donor-derived HSCs in serial transplanted mice.
Table S1. Similarities aged Lnk-/- HSCs compared with young Lnk-/- HSCs and aged WT HSCs with young WT HSCs.
Table S2. Aged Lnk-/- HSCs show depletion of cell cycle and DNA repair pathways compared to aged WT HSCs.
Table S3. Young Lnk-/- HSCs show enrichment in anabolic signaling and metabolism compared to young WT HSCs.
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