Regulation of Renal Hemodynamics and the Nitric Oxide-Arginine Pathway

Authors

  • Teresa M. Rieser VMD,

    1. Department of Clinical Studies School of Veterinary Medicine University of Pennsylvania Philadelphia, PA
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  • Cynthia M. Otto DVM, PhD

    Corresponding author
    1. Department of Clinical Studies School of Veterinary Medicine University of Pennsylvania Philadelphia, PA
      Dr. Cynthia M. Otto 3850 Spruce Street Philadelphia, PA 19104
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Dr. Cynthia M. Otto 3850 Spruce Street Philadelphia, PA 19104

Summary

Over the past ten years, nitric oxide has been shown to be important in a number of biological systems. This article is a review of the literature on nitric oxide and its affects on hemodynamics in the kidney. Nitric oxide is a major contributor to basal vasodilatory tone in the renal vasculature and systemic vasculature. It also has effects on the mechanisms which comprise the tubuloglomerular feedback loop. (Vet Emerg & Crit Care, 1998; 8: 7–18)

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