Dr. Graham's current address: Cambridge Specialist Laboratory Services, PO Box 903, Sawston, Cambridge CB2 4ZR, UK.
Serum concentrations of parathyroid hormone and 25-OH vitamin D3 in cats with urethral obstruction
Article first published online: 23 AUG 2005
Journal of Veterinary Emergency and Critical Care
Volume 15, Issue 3, pages 179–184, September 2005
How to Cite
Drobatz, K. J., Ward, C., Graham, P. and Hughes, D. (2005), Serum concentrations of parathyroid hormone and 25-OH vitamin D3 in cats with urethral obstruction. Journal of Veterinary Emergency and Critical Care, 15: 179–184. doi: 10.1111/j.1476-4431.2005.00137.x
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- acute renal failure;
- calcium metabolism;
Objective: To measure serum parathyroid hormone (PTH) and 25-hydroxyvitamin D3 concentrations in cats with urethral obstruction.
Design: Prospective single cohort study.
Setting: University affiliated veterinary teaching hospital.
Animals: Male cats with urethral obstruction.
Interventions: Routine blood samples drawn from male cats with urethral obstruction.
Measurements and main results: Measured variables included blood gas parameters, plasma sodium, potassium, chloride, and ionized calcium concentrations, as well as serum blood urea nitrogen, creatinine, phosphorus, PTH, and 25-hydroxyvitamin D3 concentrations. PTH was inversely correlated with ionized calcium and positively correlated with serum phosphorus. No discernable relationship could be found between 25-hydroxyvitamin D3 and any of the measured parameters.
Conclusions: Lack of parathyroid response does not appear to be the underlying mechanism for ionized hypocalcemia in cats with urethral obstruction.