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Thromboelastography: a tool for measuring hypercoagulability, hypocoagulability, and fibrinolysis

Authors

  • Suzanne M. Donahue VMD, DACVECC,

    1. From the 1Section of Critical Care, Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA
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  • and 1 Cynthia M. Otto DVM, PhD, DAVECC 1

    1. From the 1Section of Critical Care, Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA
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Address correspondence and reprint requests to:
Dr. Suzanne M. Donahue, Section of Critical Care, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104-6010.
E-mail: suzanned@vet.upenn.edu

Abstract

Objective: To describe the technique of thromboelastography (TEG) and review the applications of this coagulation test in humans and small animals.

Data sources: Data sources included scientific reviews and original research publications.

Human data synthesis: TEG in humans has been used for documentation of hypercoagulable and hypocoagulable states and has been shown to be beneficial in patient management.

Veterinary data synthesis: Clinical evaluation of TEG in veterinary medicine is limited; however, recent reports have documented evidence of hypercoagulability in dogs with parvovirus and protein-losing nephropathy. Additionally, many of the research models may be relevant to veterinary patients.

Conclusions: TEG provides information about coagulation that is not available through routine coagulation tests. The application of TEG monitoring to veterinary patients shows promise; however, prospective clinical studies are needed.

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