Vasopressin therapy in dogs with dopamine-resistant hypotension and vasodilatory shock
Version of Record online: 29 AUG 2007
Journal of Veterinary Emergency and Critical Care
Volume 17, Issue 4, pages 399–408, December 2007
How to Cite
Silverstein, D. C., Waddell, L. S., Drobatz, K. J. and King, L. G. (2007), Vasopressin therapy in dogs with dopamine-resistant hypotension and vasodilatory shock. Journal of Veterinary Emergency and Critical Care, 17: 399–408. doi: 10.1111/j.1476-4431.2007.00235.x
- Issue online: 29 AUG 2007
- Version of Record online: 29 AUG 2007
- antidiuretic hormone;
- central venous pressure;
- heart rate;
- mean arterial pressure
Objective: To describe the therapeutic use of vasopressin in dogs with dopamine-resistant hypotension and vasodilatory shock.
Series summary: We report the effects of intravenous vasopressin therapy on mean arterial blood pressure and central venous pressure (CVP) in 5 dogs with dopamine-resistant hypotension from vasodilatory shock. All subjects had documented hypotension and vasodilation, despite adequate intravascular volume and catecholamine therapy. There was an increase in mean arterial pressure following vasopressin administration. No cardiac arrhythmias were noted, nor were there clinically significant changes in CVP.
New information provided: Mean arterial blood pressure increased following vasopressin therapy in all of the dogs. Vasopressin may prove useful in the treatment of vasodilatory shock, however further research is warranted.