Critical illness-related corticosteroid insufficiency in a dog with septic shock
Article first published online: 15 MAY 2009
© Veterinary Emergency and Critical Care Society 2009
Journal of Veterinary Emergency and Critical Care
Volume 19, Issue 3, pages 262–268, June 2009
How to Cite
Peyton, J. L. and Burkitt, J. M. (2009), Critical illness-related corticosteroid insufficiency in a dog with septic shock. Journal of Veterinary Emergency and Critical Care, 19: 262–268. doi: 10.1111/j.1476-4431.2009.00407.x
- Issue published online: 8 JUN 2009
- Article first published online: 15 MAY 2009
- aspiration pneumonia;
- critical care;
- systemic inflammatory response syndrome
Objective – To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock.
Case Summary – A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI.
New or Unique Information Provided – This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.