The authors declare no conflicts of interest.
Incidence of seizures associated with iopamidol or iomeprol myelography in dogs with intervertebral disk disease: 161 cases (2000–2002)
Article first published online: 6 NOV 2009
© Veterinary Emergency and Critical Care Society 2009
Journal of Veterinary Emergency and Critical Care
Volume 19, Issue 6, pages 611–616, December 2009
How to Cite
Lexmaulova, L., Zatloukal, J., Proks, P., Dvorak, M., Srnec, R., Rauser, P., Kecova, H. and Necas, A. (2009), Incidence of seizures associated with iopamidol or iomeprol myelography in dogs with intervertebral disk disease: 161 cases (2000–2002). Journal of Veterinary Emergency and Critical Care, 19: 611–616. doi: 10.1111/j.1476-4431.2009.00479.x
- Issue published online: 9 DEC 2009
- Article first published online: 6 NOV 2009
- contrast radiography;
- diagnostic imaging;
- spinal cord
Objective – To compare the incidence of seizures in dogs with intervertebral disk disease after iopamidol or iomeprol myelography, and to assess whether the incidence of seizures differed between the 2 agents when severity of neurological deficits, location of cord compression, duration of anesthesia, site of myelogram, volume of contrast, and concentration of contrast were evaluated.
Design – Retrospective study.
Setting – Veterinary teaching hospital.
Animals – One hundred and sixty-one client-owned dogs with intervertebral disk disease.
Interventions – Subarachnoid injection of contrast medium.
Measurements and Main Results – One hundred and sixty-one dogs with intervertebral disk disease were subjected to myelography using iopamidol (n=74) or iomeprol (n=87). Cranial myelography was performed in 31 dogs, caudal myelography in 125 and both cranial and caudal myelography in 5. Seizures occurred in 23 of 161 (14%) dogs. There was no significant difference overall between iopamidol and iomeprol myelography. However, in dogs with thoracolumbar disk extrusion and paraplegia, seizures occurred more frequently after caudal myelography using iopamidol compared with iomeprol.
Conclusions – Both iomeprol and iopamidol are suitable for myelography in dogs. Iomeprol is recommended for caudal myelography in paraplegic dogs with thoracolumbar disk extrusion due to the higher incidence of seizures in this group when iopamidol was used.