Results from this retrospective study were presented in abstract form at the International Veterinary Emergency and Critical Care Annual Conference in Chicago on September 13, 2009.
Retrospective Study: Incidence of transfusion reactions to commercial equine plasma
Article first published online: 21 JUN 2010
© Veterinary Emergency and Critical Care Society 2010
Journal of Veterinary Emergency and Critical Care
Volume 20, Issue 4, pages 421–425, August 2010
How to Cite
Hardefeldt, L. Y., Keuler, N. and Peek, S. F. (2010), Retrospective Study: Incidence of transfusion reactions to commercial equine plasma. Journal of Veterinary Emergency and Critical Care, 20: 421–425. doi: 10.1111/j.1476-4431.2010.00545.x
The authors declare no conflicts of interest.
- Issue published online: 23 AUG 2010
- Article first published online: 21 JUN 2010
- Submitted September 22, 2009; Accepted May 6, 2010.
Objective – To report on the incidence of transfusion reactions to commercial equine plasma in a hospital-based population of horses, to characterize these reactions and report on outcome.
Design – Retrospective study.
Setting – University teaching hospital.
Animals – Client-owned horses referred to the University of Wisconsin.
Interventions – Intravenous administration of 2 commercial equine plasma products when clinically indicated.
Measurements and Main Results – Medical records of 107 horses that received plasma transfusions between 2003 and 2008 were evaluated. Transfusion reactions were recorded in 6 of 107 transfusions. All individuals were administered plasma from 1 commercial source. Foals <30 days of age received a hypergammaglobulinemic product and all adults received a lower IgG concentration product. No reactions were recorded in adults. In foals (<30 d) reactions were recorded in 6 of 69 cases (8.7%), all of which occurred in neonates <7 days of age (6/62; [9.7%]). The most frequent reactions were fever (4/6), tachycardia (2/6), tachypnea (2/6), and colic (2/6). All affected foals survived the reaction. There were no statistically significant differences (P<0.05) in any of the variables examined between those foals that did and those that did not experience transfusion reactions.
Conclusion – The incidence of transfusion reactions was 8.7% in foals and 0% in adult horses in our referral population. Five of 6 foals responded to medical therapy and eventually received the clinically indicated transfusion. No transfusion related mortality occurred.