The study was conducted at the Veterinary Clinical Department, University of Pisa, via Livornese lato monte, 56122 San Piero a Grado, Pisa, Italy.
Continuous positive airway pressure administered via face mask in tranquilized dogs
Article first published online: 29 SEP 2010
© Veterinary Emergency and Critical Care Society 2010
Journal of Veterinary Emergency and Critical Care
Volume 20, Issue 5, pages 503–508, October 2010
How to Cite
Briganti, A., Melanie, P., Portela, D., Breghi, G. and Mama, K. (2010), Continuous positive airway pressure administered via face mask in tranquilized dogs. Journal of Veterinary Emergency and Critical Care, 20: 503–508. doi: 10.1111/j.1476-4431.2010.00579.x
The authors declare no conflicts of interest.
- Issue published online: 18 OCT 2010
- Article first published online: 29 SEP 2010
- Submitted November 16, 2009; Accepted August 21, 2010.
- noninvasive ventilation (NIV);
- oxygen therapy
Objective – To evaluate the tolerance of a continuous positive airway pressure (CPAP) mask in tranquilized dogs and compare PaO2 in arterial blood in dogs receiving oxygen with a regular face mask or CPAP mask set to maintain a pressure of 2.5 or 5 cm H2O.
Design – Prospective, randomized clinical study.
Setting – University teaching hospital.
Animals – Sixteen client-owned dogs without evidence of cardiopulmonary disease were studied.
Interventions – Eight animals were randomly assigned to each of 2 treatment groups: group A received 2.5 cm H2O CPAP and group B received 5 cm H2O CPAP after first receiving oxygen (5 L/min) by a regular face mask. Animals were tranquilized with acepromazine 0.05 mg/kg, IV and morphine 0.2 mg/kg, IM. An arterial catheter was then placed to facilitate blood sampling for pHa, PaO2, and PaCO2 determinations before and after treatments. Direct mean arterial pressure, heart rate, respiratory rate, and temperature were also recorded after each treatment.
Measurements and Main Results – CPAP administration was well tolerated by all animals. The mean arterial pressure, heart rate, respiratory rate, temperature, PaCO2, and pHa, did not differ at any time point between groups. Differences were seen in oxygenation; in group A, PaO2 significantly increased from a mean of 288.3±47.5 mm Hg with a standard mask to a mean of 390.3±65.5 mm Hg with the CPAP mask and in group B, PaO2 increased similarly from 325.0±70.5 to 425.2±63.4 mm Hg (P<0.05); no differences were detected between the 2 CPAP treatments.
Conclusions – In healthy tranquilized dogs noninvasive CPAP is well tolerated and increases PaO2 above values obtained when using a regular face mask.