Abstract presented at the 15th International Veterinary Emergency and Critical Care Symposium, Chicago, IL, September 2009.
Comparison of whole blood and plasma colloid osmotic pressure in healthy dogs
Version of Record online: 5 MAY 2011
© Veterinary Emergency and Critical Care Society 2011
Journal of Veterinary Emergency and Critical Care
Volume 21, Issue 3, pages 236–241, June 2011
How to Cite
Odunayo, A. and Kerl, M. E. (2011), Comparison of whole blood and plasma colloid osmotic pressure in healthy dogs. Journal of Veterinary Emergency and Critical Care, 21: 236–241. doi: 10.1111/j.1476-4431.2011.00639.x
Dr. Odunayo current address: Department of Veterinary Clinical Sciences, Auburn University, 612 Hoerlein Hall, Auburn, AL 36849.
- Issue online: 1 JUN 2011
- Version of Record online: 5 MAY 2011
- Submitted June 21, 2010; Accepted March 29, 2011.
- clinical pathology;
- critical care;
- fluid balance;
Objective – To determine the difference between colloid osmotic pressure (COP) values determined from plasma versus those determined from whole blood.
Design – Prospective observational study.
Settings – University veterinary teaching hospital.
Animals – Fifty-three healthy dogs.
Interventions – None.
Measurements and Main Results – Whole blood and plasma COP, CBC, plasma biochemistry. In all dogs, plasma COP values were significantly lower (P=0.02) than whole blood COP, with a mean of difference of 0.5 mm Hg. The mean and median whole blood COP was 21.75 and 21.4 mm Hg, respectively, with a range of 17.9–27.1 mm Hg. The mean and median plasma COP was 21.2 and 20.9 mm Hg with a range of 16.7–28.9 mm Hg.
Conclusions – While significant difference exists between plasma and whole blood COP, the individual values are within expected reference intervals for dogs (21–25 mm Hg). Using either sample appears to provide the same information in clinically healthy dog; however, it is recommended that clinicians utilize the same sample type for comparison in an individual patient.