Funding for this study was provided by the American College of Veterinary Internal Medicine Foundation.
Presumptive bacterial translocation in horses with strangulating small intestinal lesions requiring resection and anastomosis
Version of Record online: 13 NOV 2012
© Veterinary Emergency and Critical Care Society 2012
Journal of Veterinary Emergency and Critical Care
Volume 22, Issue 6, pages 653–660, December 2012
How to Cite
Hurcombe, S. D., Mudge, M. C. and Daniels, J. B. (2012), Presumptive bacterial translocation in horses with strangulating small intestinal lesions requiring resection and anastomosis. Journal of Veterinary Emergency and Critical Care, 22: 653–660. doi: 10.1111/j.1476-4431.2012.00803.x
The authors declare no conflict of interests.
- Issue online: 6 DEC 2012
- Version of Record online: 13 NOV 2012
- Manuscript Accepted: 2 AUG 2012
- Manuscript Received: 30 JUN 2011
- American College of Veterinary Internal Medicine Foundation
- antimicrobial therapy;
- intestinal surgery
To document whether presumptive bacterial translocation (PBT) occurs in horses with small intestinal strangulation (SIS).
Prospective clinical cohort study.
University tertiary care facility.
Thirty-six adult horses with SIS (clinical cases) and 10 adult horses without gastrointestinal disease (control cases).
Sterile collection and bacterial culture of samples from peripheral venous blood, mesenteric venous blood, mesenteric lymphatic tissue, and intestinal aspirates from horses with SIS and control horses without gastrointestinal disease.
Measurements and Main Results
Five of 36 (13.8%) horses with SIS had at least 1 sample yield a positive result. Shorter SIS bowel segments were more likely to yield a positive culture result. (P < 0.01). Two of 10 of control horses had positive culture results with different bacterial species identified compared to horses with SIS. Antimicrobial usage did not influence bacterial culture status (P = 0.31). There were no differences between culture-positive and culture-negative horses with SIS regarding admission, clinical, or clinicopathologic variables.
PBT occurs in normal horses and in horses with SIS. Bacterial genera differed between groups. A low incidence of PBT occurs in horses with SIS suggesting postoperative morbidity in some cases may be due to other factors.