THE EFFECTS OF ATROPINE AND OXOTREMORINE ON ACETYLCHOLINE RELEASE IN RAT PHRENIC NERVE-DIAPHRAGM PREPARATIONS
Version of Record online: 19 JUL 2012
1981 British Pharmacological Society
British Journal of Pharmacology
Volume 73, Issue 2, pages 481–483, June 1981
How to Cite
ABBS, E.T. and JOSEPH, D.N. (1981), THE EFFECTS OF ATROPINE AND OXOTREMORINE ON ACETYLCHOLINE RELEASE IN RAT PHRENIC NERVE-DIAPHRAGM PREPARATIONS. British Journal of Pharmacology, 73: 481–483. doi: 10.1111/j.1476-5381.1981.tb10446.x
- Issue online: 19 JUL 2012
- Version of Record online: 19 JUL 2012
- Received September 29, 1980; Revised October 30, 1980
- 1Atropine (10−5m) enhanced the release of [3H]-acetylcholine from rat isolated hemidiaphragms, previously incubated with [3H-methyl]-choline, stimulated via their phrenic nerves.
- 2Oxotremorine (10−5m) did not affect the stimulated release of [3H]-acetylcholine but antagonized the facilitatory effects of atropine (10−5m).
- 3It is suggested that there are presynaptic inhibitory muscarinic receptors that modulate the release of acetylcholine in the phrenic nerves of the rat.