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  • 1
    Extracellular single neurone recordings were made in the ventrobasal thalamus of urethaneanaesthetized rats.
  • 2
    Iontophoretically and intravenously administered ketamine and MK-801 were found to be selective antagonists of responses of neurones to iontophoretically applied N-methylaspartate.
  • 3
    Both antagonists, administered in N-methylaspartate-selective quantities, reduced the synaptic responses of ventrobasal thalamus neurones to a two-second air jet directed at the peripheral receptive field.