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  • AMARAL, D.G. & SINNAMON, H.M. (1977). The locus coeruleus: neurobiology of a central noradrenergic nucleus. Prog. Neurobiol., 9, 147158.
  • APORTI, F., BORSATO, R., CALDERINI, G., RUBINI, R., TOFFANO, G., ZANOTTI, A., VALZELLI, L. & GOLDSTEIN, L. (1986). Age-dependent spontaneous EEG bursts in rats: effects of brain phosphatidylserine. Neurobiol. of Aging, 7, 115120.
  • APORTI, F., NELSEN, J.M. & GOLDSTEIN, L. (1982). A quantitative EEG study at cortical and subcortical levels of the effects of brain cortical phosphatidylserine (BC-PS) in rats, and of its interaction with scopolamine. Res. Comm. Psychol. Psychiat. Behaviour, 7, 131143.
  • ASTON-JONES, G. & BLOOM, F.E. (1981a). Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli. J. Neurosci., 1, 887900.
  • ASTON-JONES, G. & BLOOM, F.E. (1981b). Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleepwaking cycle. J. Neurosci., 1, 876886.
  • BONETTI, A., BATTISTELLA, A., CALDERINI, G., TEOLATO, S., CREWS, F.T., GAITI, A., ALGERI, S. & TOFFANO, G. (1983). Biochemical alterations in the mechanisms of synaptic transmission in aging brain In The Aging of the Brain, ed. Samuel, D., Algeri, S., Gershon, S., Grimm, V.E. & Toffano, G. pp. 171181. New York: Raven Press.
  • BONETTI, A., BELLINI, F., CALDERINI, G., GALBIATI, E. & TOFFANO, G. (1987). Age-dependent changes in the mechanisms controlling prolactin secretion and phosphatidylinositol turnover in male rats: effect of phosphatidylserine. Neuroendocrinology, 45, 123129.
  • BRICOLO, A., TURAZZI, S., FACCIOLI, F., ODORIZZI, F., SCIARRETTA, C. & ERCULIANI, P. (1978). Clinical application of compressed spectral array in long-term EEG monitoring of comatose patients. Electroenceph. Clin. Neurophysiol., 45, 211255.
  • BRODDE, O.E., ANLAUF, M., GRABEN, N. & BOCK, K.D. (1982). Age-dependent decrease of α2-adrenergic receptor number in human platelets. Eur. J. Pharmacol., 81, 345347.
  • BRUNI, A. & TOFFANO, G. (1982). The principles of phospholipid pharmacology In Transport in Biomembranes: Model Systems and Reconstitution, ed. Antolini, R., Gliozzi, A. & Gorio, A. pp. 235242. New York: Raven Press.
  • BURCHINSKY, S.G. (1984). Neurotransmitter receptors in the central nervous system and aging: Pharmacological aspect (Review). Exp. Gerontol., 29, 227239.
  • CALDERINI, G., BONETTI, A.C., BATTISTELLA, A., CREWS, F. T. & TOFFANO, G. (1983). Biochemical changes of rat brain membranes with aging. Neurochem. Res., 8, 483492.
  • CASAMENTI, F., MANTOVANI, P., AMADUCCI, L. & PEPEU, G. (1979). Effect of phosphatidylserine on acetylcholine output from the cerebral cortex of the rat. J. Neurochem., 32, 529533.
  • CEDARBAUM, J.M. & AGHAJANIAN, G.K. (1977). Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization. Eur. J. Pharmacol., 44, 375385.
  • CESPUGLIO, R., GOMEZ, M.E., FARADJI, H. & JOUVET, M. (1982). Alterations in the sleep-waking cycle induced by cooling of the locus coeruleus area. Electroenceph. Clin. Neurophysiol., 54, 570578.
  • CLARK, T.K. (1979). The locus coeruleus in behavior regulation: evidence for behavior-specific versus general involvement. Behav. Neural Biol., 25, 271294.
  • CREWS, F.T., CALDERINI, G., BATTISTELLA, A. & TOFFANO, G. (1981). Age-dependent changes in the methylation of rat brain phospholipids. Brain Res., 299, 256259.
  • DAHLSTROM, A. & FUXE, K. (1964). Evidence for the existence of monoamine containing neurons in the central nervous system. I. Demonstration of monoamine in the cell bodies of brain stem neurons. Acta Physiol. Scand., 232, 155.
  • DE SARRO, G.B., ASCIOTI, C., FROIO, F., LIBRI, V. & NISTICO, G. (1987a). Evidence that locus coeruleus is the site where clonidine and drugs acting at α1- and α2-adrenoceptors affect sleep and arousal mechanisms. Br. J. Pharmacol., 90, 675685.
  • DE SARRO, G.B., BAGETTA, G., FILASTRO, F., FERSINI, G. & NISTICO, G. (1987b). ECoG spectrum power alterations in old rats are reversed by phosphatidylserine In New Trends in Aging Research ed. Pepeu, G. p. 86.Padova: Liviana Press.
  • DI RENZO, G., AMOROSO, S., TAGLIATELA, M., CALDERINI, G., GALBIATI, E. & ANNUNZIATO, L. (1987). Prolonged exposure of pituitary dopaminergic receptors to the phospholipid phosphatidylserine increases their sensitivity to dopamine in aged rats. Neuroendocrinal. Lett., 9, 5156.
  • DOCHERTY, J.R. & HYLAND, L. (1986). Aging and α-adrenoceptor function. Trends Pharmacol. Sci., 7, 131132.
  • FLEISCH, J.H. (1981). Agerelated decrease in beta-adrenoceptor activity of the cardiovascular system. Trends Pharmacol. Sci., 2, 337339.
  • GAITI, A., GATTI, C., BRUNETTI, M., TEOLATO, S., CALDERINI, G. & PORCELLATI, G. (1985). Phospholipase activities in rat brain areas during aging In Phospholipids in the Nervous System, Physiological Roles, ed. Harrocks, L.A., Kaufer, J. & Porcellati, G. pp. 155162. New York: Raven Press.
  • GAITI, A., SITKIEWICZ, D., BRUNETTI, M. & PORCELLATI, G. (1981). Phospholipid metabolism in neuronal and glial cells during aging. Neurochem. Res., 6, 1322.
  • GAITI, A., BRUNETTI, M., GATTI, C. & PORCELLATI, G. (1984). Turnover of ethanolamine phosphoglycerides in different brain areas of adult and aged rats. Neurochem. Res., 9, 15491558.
  • GATTI, C., CANTELMI, M.G., BRUNETTI, M., GAITI, A., CALDERINI, G. & TEOLATO, S. (1985). Effect of chronic treatment with phosphatidylserine on phospholipase A1 and A2 activities in different brain areas of 4 months and 24 months old rats. Il Farmaco, 40, 493500.
  • HAMILTON, C.A., HOWE, C.A. & REID, J.L. (1984). Changes in brain α2-adrenoceptors with increasing age in rabbits. Brain Res., 322, 177179.
  • LEON, A., BENVEGNU, D., TOFFANO, G., ORLANDO, P. & MASSARI, P. (1978). Effect of brain cortex phospholipids on adenylate-cyclase activity of mouse brain. J. Neurochem., 30, 2326.
  • MAZZARI, S. & BATTISTELLA, A. (1980). Phosphatidylserine effect of dopamine release from striatum symaptosomes In A Multidisciplinary Approach to Brain Development, ed. DI Benedetto, C. pp. 145154. Amsterdam: Elsevier.
  • MISRA, C.H., SHELAT, H.S. & SMITH, R.C. (1980). Effect of age on adrenergic and dopaminergic receptor binding in rat brain. Life Sci., 27, 521526.
  • MOORE, K.Y. & CARD, J.P. (1984). Noradrenaline-containing neurons system In Handbook of Chemical Neuroanatomy. Classical Transmitters in the CNS Part I. ed. Björklund, T. & Hökfelt, T. pp. 123156. Amsterdam: Elsevier.
  • NAGY, K., SIMON, P. & NAGY, I. (1983). Spike label studies on synaptosomal membranes of rat brain cortex during aging. Biochem. Biophys. Res. Commun., 117, 688694.
  • PAXINOS, G. & WATSON, C. (1982). The Rat Brain in Stereotaxic Coordinates London: Academic Press.
  • PEPEU, G., GIVANNELLI, L., GIOVANNINI, M.G. & PEDATA, F. (1986). Effect of phosphatidylserine on cortical acetylcholine release and calcium uptake in adult and aging rat In Phospholipid Research and Nervous System: Biochemical and Molecular Pharmacology, ed. Harrocks, L.A., Freysz, L. & Toffano, G. pp. 265271. Padova: Liviana Press.
  • PEPEU, G., GORI, G. & BARTOLINI, L. (1980). Pharmacologic and therapeutic perspectives on dementia: An experimental approach. In: Aging of the Brain and Dementia, ed. Amaducci, L., Davison, A.N. & Antuono, P. pp. 271274. New York: Raven Press.
  • RAMM, P. (1979). The locus coeruleus, catecholamines and REM sleep: A critical review. Behav. Neural. Biol., 26, 415448.
  • SCHROEDER, F. (1985). Role of membrane lipid asymmetry in aging. Neurobiol. of Aging, 5, 323333.
  • STERIADE, M. & HOBSON, J.A. (1976). Neuronal activity during the sleep-waking cycle. Prog. Neurobiol., 6, 155376.
  • SWANSON, L.W. & HARTMAN, B.K. (1975). The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-β-hydroxylase as a marker. J. Comp. Neurol., 163, 467506.
  • TALLARIDA, R.J. & MURRAY, R.B. (1981). Manual of Pharmacological Calculations with Computer Programs. Berlin: Springer-Verlag.
  • TOFFANO, G. (1985). Membrane lipid changes and modification of neuronal function homeostasis in aging brain. Neurobiol. Aging, 5, 341343.
  • TOFFANO, G. & BRUNI, A. (1980). Pharmacological property of phospholipid liposome. Pharmacol. Res. Commun., 12, 829845.
  • ZAULI, C., BONURA, M.L., GIOVALE, M., DE MARIA, A., MASTURZO, P., MURIALDO, G., POLLERI, A. & TOFFANO, G. (1984). Evidence for a dopaminergic inhibitory effect of orally-administered phosphatidylserine on prolactin secretion in humans. Neuroendocrinol. Lett., 6, 3747.