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  • ABI-DARGHAM, A., LARUELLE, M., WONG, D.T., ROBERTSON, D.W., WEINBERGER, D.R., & KLEINMAN, J.E. (1993). Pharmacological and regional characterization of [3H]LY278584 binding sites in human brain. J. Neurochem., 60, 730737.
  • BARNES, J.M., BARNES, N.M., COSTALL, B., IRONSIDE, J.W. & NAYLOR, R.J. (1989). Identification and characterisation characterization of 5-hydroxytryptamine3 recognition sites in human brain tissue. J. Neurochem., 53, 17871793.
  • BELELLI, D., BALCAREK, J.M., HOPE, A.G., PETERS, J.A., LAMBERT, J.J. & BLACKBURN, T.P. (1995). Cloning and functional expression of a human 5-hydroxytryptamine type3AS receptor (5-HT3R-AS) subunit. Mol. Pharmacol., 48, 10541062.
  • BOESS, F.G. & MARTIN, I.L (1994). Molecular biology of 5-HT receptors. Neuropharmacology, 33, 275317.
  • BOESS, F.G., SEPÚLVEDA, M.-I., LUMMIS, S.C.R., AND MARTIN, I.L. (1992). 5-HT3 receptors in NG108–15 neuroblastoma x glioma cells: effect of the novel agonist 1-(m-chlorophenyl)-biguanide. Neuropharmacology, 31, 561564.
  • BONHAUS, D.W., STEFANICH, E., LOURY, D.N., HSU, S.A.O., EGLEN, R.M. & WONG, E.H.F. (1995). Allosteric interactions among agonists and antagonists at 5-hydroxytryptamine3 receptors. J. Neurochem., 65, 104110.
  • BONHAUS, D.W., WONG, E.H.F., STEFANICH, E., KUNYSZ, E.A. & EGLEN, R.M. (1993). Pharmacological characterization of 5-hydroxytryptamine3 receptors in murine brain and ileum using the novel radioligand [3H]RS-42358–197: evidence for receptor heterogeneity. J. Neurochem., 61, 19271932.
  • BUFTON, K.E., STEWARD, L.J., BARBER, P.C. & BARNES, N.M. (1993). Distribution and characterization of the [3H]granisetron-labelled 5-HT3 receptor in the human forebrain. Neuropharmacology, 32, 13251331.
  • BUTLER, A., ELSWOOD, C.J., BURRIDGE, J., IRELAND, S.J., BUNCE K.T., KILPATRICK, G.J. & TYERS, M.B. (1990). The pharmacological characterization of 5-HT3 receptors in three isolated preparations derived from guinea-pig tissues. Br. J. Pharmacol., 101, 591598.
  • CHENG, Y. & PRUSOFF, W.H. (1973). Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50% inhibition (IC50) of an enzymatic reaction. Biochem. Pharmacol., 22, 30993108.
  • CHIRGWIN, J.M., PRZYBYLA, A.E., MACDONALD, R.J. & RUTTER, W.J. (1979). Isolation of a biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18, 52945299.
  • DEMPSTER, J. (1993). Computer Analysis of Electrophysiological Signals. London: Academic Press.
  • DERKACH, V., SURPRENANT, A. & NORTH, R.A. (1989). 5-HT3 receptors are membrane ion channels. Nature, 339, 706709.
  • DOWNIE, D.L., HOPE, A.G., BELELLI, D., LAMBERT, J.J., PETERS, J.A., BENTLEY, K.R., STEWARD, L.J., CHEN, C.-Y. & BARNES, N.M. (1995). The interaction of trichloroethanol with murine recombinant 5-HT3 receptors. Br. J. Pharmacol., 114, 16411651.
  • DOWNIE, D.L., HOPE, A.G., LAMBERT, J.J., PETERS, J.A., BLACKBURN, T.P. & JONES, B.J. (1994). Pharmacological characterization of the apparent splice variants of the murine 5-HT3 R-A subunit expressed in Xenopus laevis oocytes. Neuropharmacology, 33, 473482.
  • EISELÉM J.-L., BERTRAND, S., GALZI, J.-L., DEVILLERS-THIÉRY, A., CHANGEUX, J.-P. & BERTRAND, D. (1993). Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature, 366, 479483.
  • FEINBERG, A.P. & VOGELSTEIN, B. (1983). A technique for radiolabelling restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 613.
  • FLETCHER, S. & BARNES, N.M. (1995). Solubilisation of the 5-HT3 receptor recognition site expressed in pig cerebral cortex. Br. J. Pharmacol., 116, 230P.
  • FOZARD, J.R. (1983). Differences between receptors for 5-hydroxytryptamine on autonomic neurones revealed by nor (−)−cocaine. J. Autonom. Pharmacol., 3, 2126.
  • FOZARD, J.R. (1984). MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 326, 3644.
  • GILL, C.H., PETERS, J.A. & LAMBERT, J.J. (1995). An electrophysiological investigation of the properties of a murine recombinant 5-HT3 receptor stably expressed in HEK 293 cells. Br. J. Pharmacol., 114, 12111221.
  • HARRISON, T., GRAHAM F. & WILLIAMS, J. (1977). Host-range mutants of adenovirus type 5 defective for growth in HeLa cells. Virology, 77, 319329.
  • HOPE, A.G., BROWN, A.M., PETERS, J.A., LAMBERT, J.J., BALCAREK, J.M. & BLACKBURN, T.P. (1995). Characterisation of a cloned human 5-HT3 receptor subunit stably expressed in HEK-293 cells. Br. J. Pharmacol., 116, 82P.
  • HOPE, A.G., DOWNIE, D.L., SUTHERLAND, L., LAMBERT, J.J., PETERS, J.A. & BURCHELL, B. (1993). Cloning and functional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit. Eur. J. Pharmacol. (Mol. Pharmacol. Sect.), 245, 187192.
  • HOYER, D., CLARKE, D.E., FOZARD, J.R., HARTIG, P.R., MARTIN, G.R., MYLECHARANE, E.J., SAXENA, P.R. & HUMPHREY, P.P.A. (1994). VII. International Union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev., 46, 157203.
  • HUSSY, N., LUKAS, W. & JONES, K.A. (1994). Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors. J. Physiol., 418, 311323.
  • ISENBERG, K.E., UKHUN, I.A., HOLSTAD, S.G., JAFRI, S., UCHIDA, U., ZORUMSKI, C.F. & YANG, J. (1993). Partial cDNA cloning and NGF regulation of a rat 5-HT3 receptor subunit. NeuroReport, 5, 121124.
  • JACKSON, M.B. & YAKEL, J.L. (1995). The 5-HT3 receptor channel. Annu. Rev. Physiol., 57, 447468.
  • JOHNSON, D.S. & HEINEMANN, S.F. (1992). Cloning and expression of the rat 5-HT3 receptor reveals species specific sensitivity to curare antagonism. Soc. Neurosci. Abs., 18, p. 249, 11513.
  • KILPATRICK, G.J., BARNES, N.M., CHENG, C.H.K., COSTALL, B., NAYLOR, R.J. & TYERS, M.B. (1991). The pharmacological characterization of 5-HT3 receptor binding sites in rabbit ileum: comparision with those in rat ileum and rat brain. Neurochem. Int., 19, 389396.
  • KILPATRICK, G.J., BUTLER, A., HAGAN, R.M., JONES, B.J. & TYERS, M.B. (1990). [3H] GR67330, a very high affinity ligand for 5-HT3 receptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 342, 2230.
  • LAMBERT, J.J., PETERS, J.A. & HOPE, A.G. (1995). ‘5-HT3 receptors’. In Ligand and Voltage-Gated Ion Channels ed. North, R.A., pp. 177211. Boca Raton: CRC Press.
  • LEADER, D.P., GALL, I. & LEHRACH, H. (1985). The structure of a cloned mouse γ actin processed pseudogene. Gene, 36, 369374.
  • LOWRY, O.H., ROSEBROUGH, N.J., FARR, A.L. & RANDALL, R.J. (1951). Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265275.
  • MALONE, H.M., PETERS, J.A. & LAMBERT, J.J. (1991). Physiological and pharmacological properties of 5-HT3 receptors - a patchclamp study. Neuropeptides, 19, 2530.
  • MARICQ, A.V., PETERSON, A.S., BRAKE, A.J., MYERS, R.M. & JULIUS, D. (1991). Primary structure and functional expression of the 5-HT3 receptor, a serotonin-gated ion channel. Science, 254, 432437.
  • MAURA, G., ANDRIOLI, G.C., CAVAZZANI, P. & RAITERI, M. (1992). 5-Hydroxytryptamine3 receptors sited on cholinergic axon terminals of the human cerebral cortex mediate inhibition of acetylcholine release. J. Neurochem., 58, 23342337.
  • MIYAKE, A., MOCHIZUKI, S., TAKEMOTO, Y. & AKUZAWA, S. (1995). Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species. Mol. Pharmacol., 48, 407416.
  • MORAIN, P., ABRAHAM, C., PORTEVIN, B. & DeNANTEEUIL, G. (1994). Biguanide derivatives: agonist pharmacology at 5-hydroxytryptamine type 3 receptors in vitro. Mol. Pharmacol., 46, 732742.
  • NELSON, D.R. & THOMAS, D.R. (1989). [3H] BRL 43694 (granisetron), a specific ligand for 5-HT3 binding sites in rat brain. Biochem. Pharmacol., 38, 16931695.
  • NEWBERRY, N.R., CHESHIRE, S.H. & GILBERT, M.J. (1991). Evidence that the 5-HT3 receptors of the rat, mouse and guinea-pig superior cervical ganglion may be different. Br. J. Pharmacol., 102, 615620.
  • PERREN, M.J., ROGERS, H., MASON, G.S., BULL, D.R. & KILPATRICK, G.J. (1995). A pharmacological comparison of [3H]-granisetron binding sites in brain and peripheral tissues of the mouse. Naunyn-Schmiedeberg's Arch. Pharmacol., 351, 211228.
  • PETERS, J.A., LAMBERT, J.J. & MALONE, H.M. (1994). Electrophysiological studies of 5-HT3 receptors, in 5-Hydroxytryptamine-3 Receptor Antagonists ed. King, F.D., Jones, B.J. & Sanger, G.J. pp. 115153, Boca Raton: CRC Press.
  • PETERS, J.A., MALONE, H.M. & LAMBERT, J.J. (1992). Recent advances in the electrophysiological characterization of 5-HT3 receptors. Trends Pharmacol. Sci., 13, 391397.
  • PETERS, J.A., MALONE, H.M. & LAMBERT, J.J. (1991). Characterization of 5-HT3 receptor mediated electrical responses in nodose ganglion neurones and clonal neuroblastoma cells maintained in culture. In Serotonin: Molecular Biology, Receptors and Functional Effects. ed. Fozard, J.R. & Saxena, P.R. pp. 8494, Basel: Birkhauser.
  • RICHARDSON, B.P. & ENGEL, G. (1986). The pharmacology and function of 5-HT3 receptors. Trends Pharmacol. Sci., 9, 424428.
  • RICHARDSON, B.P., ENGEL, G., DONATSCH, P. & STADLER, P.A. (1985). Identification of serotonin M-receptor subtypes and their blockade by a new class of drugs. Nature, 316, 126131.
  • SAMBROOK, J., FRITSCH, E.F. & MANIATIS, T. (1989). Molecular Cloning: A Laboratory Manual (Second Edition). ed. Nolan, C. New York: Cold Spring Harbor Press.
  • SANGER, G.J. & JONES, B.J. (1994). Assay techniques for measuring 5-HT3 receptor antagonist activity. In 5-Hydroxytryptamine-3 Receptor Antagonists ed. King, F.D., Jones, B.J. & Sanger, G.J. pp. 6778, Boca Raton: CRC Press.
  • SEPULVEDA, M.-I., LUMMIS, S.C.R. & MARTIN, I.L. (1991). The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT3 receptors in N1E-115 cells. Br. J. Pharmacol., 104, 536540.
  • SCHULTE, M.K., BLOOM, K.E. & WHITE, M.M. (1995). Evidence for the involvement of tryptophan in the binding of curare to 5-HT3 receptors. Soc. Neurosci. Abs. 21, 3036.
  • STEWARD, J.L., GE, J., BENTLEY, K.R., BARBER, P.C., HOPE, A.G., LAMBERT, J.J., PETERS, J.A., BLACKBURN, T.P. & BARNES, N.M. (1995). Evidence that the atypical 5-HT3 receptor ligand, [3H] BRL46470, labels additional 5-HT3 receptor binding sites compared to [3H]-granisetron. Br. J. Pharmacol., 116, 17811788.
  • WONG, E.H.F., BONHAUS, D.W., LEE, J.A., WU, I., LOURY, A.N. & EGLEN, R.M. (1993a). Different densities of 5-HT3 receptors are labeled by [3H]quipazine, [3H]GR 65630 and [3H]granisetron. Neuropharmacology, 32, 869875.
  • WONG, E.H.F., BONHAUS, D.W., WU, I., STEFANICH, E. & EGLEN, R.M. (1993b). Labelling of 5-hydroxytryptamine3 receptors with a novel 5-HT3 receptor ligand, [3H]RS-42358–197. J. Neurochem., 60, 921930.
  • WONG, E.H.F., CLARK, R., LEUNG, E., LOURY, D., BONHAUS, D.W., JAKEMAN, L., PARNES, H., WHITING, R.L. & EGLEN, R.M. (1995). The interaction of RS 25259–197, a potent and selective antagonist, with 5-HT3 receptors, in vitro. Br. J. Pharmacol., 114, 851859.