SEARCH

SEARCH BY CITATION

References

  • Anderson DJ, Bunnelle WH, Surber BW, Du J, Surowy CS, Tribollet E (2008). [3H]A-585539[(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo [2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain. J Pharmacol Exp Ther 324: 179187.
  • Alexander SPH, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd edn. Br J Pharmacol 153 (Suppl. 2): S1S209.
  • Bertrand D, Gopalakrishnan M (2007). Allosteric modulation of nicotinic acetylcholine receptors. Biochem Pharmacol 74: 11551163.
  • Bettany JH, Levin ED (2001). Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze. Pharmacol Biochem Behav 70: 467474.
  • Bitner RS, Bunnelle WH, Anderson DJ, Briggs CA, Buccafusc OJ, Curzon P et al. (2007). Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways. J Neurosci 27: 1057810587.
  • Bodnar AL, Cortes-Burgos LA, Cook KK, Dinh DM, Groppi VE, Hajos M et al. (2005). Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem 48: 905908.
  • Boess FG, De Vry J, Erb C, Flessner T, Hendrix M, Luithle J et al. (2007). The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents. J Pharmacol Exp Ther 321: 716725.
  • Curzon P, Anderson DJ, Nikkel AL, Fox GB, Gopalakrishnan M, Decker MW et al. (2006). Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment. Neurosci Lett 410: 1519.
  • Dajas-Bailador F, Wonnacott S (2004). Nicotinic acetylcholine receptors and the regulation of neuronal signalling. Trends Pharmacol Sci 25: 317324.
  • Dickinson JA, Hanrott KE, Mok MH, Kew JN, Wonnacott S (2007). Differential coupling of alpha7 and non-alpha7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells. J Neurochem 100: 10891096.
  • Dickinson JA, Kew JN, Wonnacott S (2008). Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms. Mol Pharmacol 74: 348359.
  • El Kouhen R, Hu M, Anderson DJ, Li J, Gopalakrishnan M (2009). Pharmacology of α7 Nicotinic acetylcholine receptor mediated extracellular signal-regulated kinase signaling in pc12 cells. Br J Pharmacol 156: 638648.
  • Felix R, Levin ED (1997). Nicotinic antagonist administration into the ventral hippocampus and spatial working memory in rats. Neuroscience 81: 10091017.
  • Faghih R, Gopalakrishnan SM, Gronlien JH, Malysz J, Briggs CA, Wetterstrand C et al. (2009). Discovery of A-867744 as a novel positive allosteric modulator of the a7 nicotinic acetylcholine Receptor. J Med Chem 52 (10): 33773384.
  • Grønlien JH, Håkerud M, Ween H, Thorin-Hagene K, Briggs CA, Gopalakrishnan M et al. (2007). Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes. Mol Pharmacol 72 (3): 715724.
  • Hogg RC, Bertrand D (2004). Nicotinic acetylcholine receptors as drug targets. Curr Drug Targets CNS Neurol Disord 3: 123130. Review.
  • Hu M, Schurdak ME, Puttfarcken PS, El Kouhen R, Gopalakrishnan M, Li J (2007). High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands. Brain Res 1151: 227235.
  • Hu M, Waring JF, Gopalakrishnan M, Li J (2008). Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells. J Neurochem 106: 13711377.
  • Hurst RS, Hajós M, Raggenbass M, Wall TM, Higdon NR, Lawson JA et al. (2005). A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J. Neurosci 25: 43964405.
  • Malysz J, Gronlien JH, Anderson DJ, Haakerud M, Thorin-Hagene K, Ween H et al. (2009). In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 nAChR, A-867744, exhibiting unique pharmacological profile. J Pharmacol Exp Ther 330 (1): 257267.
  • Miret S, De Groene EM, Klaffke W (2006). Comparison of in vitro assays of cellular toxicity in the human hepatic cell line HepG2. J Biomol Screen 11: 184193.
  • Ng HJ, Whittemore ER, Tran MB, Hogenkamp DJ, Broide RS, Johnstone TB et al. 2007. Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators. Proc Natl Acad Sci USA 104, 80598064.
  • Orr-Urtreger A, Broide RS, Kasten MR, Dang H, Dani JA, Beaudet AL et al. (2000). Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth. J Neurochem 74: 21542166.
  • Pichat P, Bergis OE, Terranova JP, Urani A, Duarte C, Santucci V et al. (2007). SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia. Neuropsychopharmacology 32: 1734.
  • Ren K, Puig V, Papke RL, Itoh Y, Hughes JA, Meyer EM (2005). Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells. J Neurochem 94: 926933.
  • Steiner RC, Heath CJ, Picciotto MR (2007). Nicotine-induced phosphorylation of ERK in mouse primary cortical neurons: evidence for involvement of glutamatergic signaling and CaMKII. J Neurochem 103: 666678.
  • Timmermann DB, Grønlien JH, Kohlhaas KL, Nielsen E. Ø., Dam E, Jørgensen TD et al. (2007). An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. J Pharmaco Exp Ther 323: 294307.
  • Van Kampen M, Selbach K, Schneider R, Schiegel E, Boess F, Schreiber R (2004). AR-R 17779 improves social recognition in rats by activation of nicotinic alpha7 receptors. Psychopharmacology (Berl) 172: 375383.
  • Wishka DG, Walker DP, Yates KM, Reitz SC, Jia S, Myers JK et al. (2006). Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure – activity relationship. J Med Chem 49: 44254436.
  • Woods DC, Liu HK, Nishi Y, Yanase T, Johnson AL (2008). Inhibition of proteosome activity sensitizes human granulosa tumor cells to TRAIL-induced cell death. Cancer Lett 260: 2027.