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References

  • Bailey CH, Bartsch D, Kandel ER (1996). Toward a molecular definition of long-term memory storage. Proc Natl Acad Sci USA 93: 1344513452.
  • Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E (1998). Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc Natl Acad Sci USA 95: 1502015025.
  • Bourtchouladze R, Lidge R, Catapano R, Stanley J, Gossweiler S, Romashko D et al. (2003). A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4. Proc Natl Acad Sci USA 100: 1051810522.
  • Bruno O, Romussi A, Spallarossa A, Brullo C, Schenone S, Bondavalli F et al. (2009). New selective phosphodiesterase 4D inhibitors differently acting on long, short, and supershort isoforms. J Med Chem 52: 65466557.
  • Burgin AB, Magnusson OT, Singh J, Witte P, Staker BL, Bjornsson JM et al. (2010). Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety. Nat Biotechnol 28: 6370.
  • Cheng YF, Wang C, Lin HB, Li YF, Huang Y, Xu JP et al. (2010). Inhibition of phosphodiesterase-4 reverses memory deficits produced by Abeta25-35 or Abeta1-40 peptide in rats. Psychopharmacology (Berl) 212: 181191.
  • Cherry JA, Davis RL (1999). Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect. J Comp Neurol 407: 287301.
  • Comery TA, Martone RL, Aschmies S, Atchison KP, Diamantidis G, Gong X et al. (2005). Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 25: 88988902.
  • Costa DA, Cracchiolo JR, Bachstetter AD, Hughes TF, Bales KR, Paul SM et al. (2007). Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiol Aging 28: 831844.
  • Ennaceur A, Delacour J (1988). A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data. Behav Brain Res 31: 4759.
  • Fedele E, Varnier G, Raiteri M (1997). In vivo microdialysis study of GABA(A) and GABA(B) receptors modulating the glutamate receptor/NO/cyclic GMP pathway in the rat hippocampus. Neuropharmacology 36: 14051415.
  • Fedele E, Varnier G, Ansaldo MA, Raiteri M (1998). Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release. Br J Pharmacol 125: 10421048.
  • Frey U, Huang YY, Kandel ER (1993). Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science 260: 16611664.
  • Giorgi M, Modica A, Pompili A, Pacitti C, Gasbarri A (2004). The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task. Behav Brain Res 154: 99106.
  • Gong B, Vitolo OV, Trinchese F, Liu S, Shelanski M, Arancio O (2004). Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment. J Clin Invest 114: 16241634.
  • Grill HJ, Norgren R (1978). The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Res 143: 263279.
  • Haass C, Selkoe DJ (2007). Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8: 101112.
  • Hebenstreit GF, Fellerer K, Fichte K, Fischer G, Geyer N, Meya U et al. (1989). Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine. Pharmacopsychiatry 22: 156160.
  • Hirose R, Manabe H, Nonaka H, Yanagawa K, Akuta K, Sato S et al. (2007). Correlation between emetic effect of phosphodiesterase 4 inhibitors and their occupation of the high-affinity rolipram binding site in Suncus murinus brain. Eur J Pharmacol 573: 9399.
  • Houslay MD, Adams DR (2003). PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J 370: 118.
  • Huang YY, Kandel ER (1994). Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization. Learn Mem 1: 7482.
  • Lamontagne S, Meadows E, Luk P, Normandin D, Muise E, Boulet L et al. (2001). Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey. Brain Res 920: 8496.
  • Li YF, Cheng YF, Huang Y, Conti M, Wilson SP, O'Donnell JM et al. (2011). Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling. J Neurosci 31: 172183.
  • Mori F, Pérez-Torres S, De Caro R, Porzionato A, Macchi V, Beleta J et al. (2010). The human area postrema and other nuclei related to the emetic reflex express cAMP phosphodiesterases 4B and 4D. J Chem Neuroanat 40: 3642.
  • Nguyen PV, Abel T, Kandel ER (1994). Requirement of a critical period of transcription for induction of a late phase of LTP. Science 265: 11041107.
  • Parker LA, Limebeer CL (2006). Conditioned gaping in rats: a selective measure of nausea. Auton Neurosci 129: 3641.
  • Paxinos G, Watson C (1986). The Rat Brain in Stereotaxic Coordinates. Academic Press: San Diego, CA.
  • Perez-Torres S, Miro X, Palacios JM, Cortes R, Puigdomenech P, Mengod G (2000). Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and[3H]rolipram binding autoradiography. Comparison with monkey and rat brain. J Chem Neuroanat 20: 349374.
  • Puzzo D, Privitera L, Leznik E, Fa M, Staniszewski A, Palmeri A et al. (2008). Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. J Neurosci 28: 1453714545.
  • Reneerkens OA, Rutten K, Steinbusch HW, Blokland A, Prickaerts J (2009). Selective phosphodiesterase inhibitors: a promising target for cognition enhancement. Psychopharmacology (Berl) 202: 419443.
  • Robichaud A, Savoie C, Stamatiou PB, Tattersall FD, Chan CC (2001). PDE4 inhibitors induce emesis in ferrets via a noradrenergic pathway. Neuropharmacology 40: 262269.
  • Robichaud A, Stamatiou PB, Jin SL, Lachance N, MacDonald D, Laliberte F et al. (2002). Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis. J Clin Invest 110: 10451052.
  • Rock EM, Benzaquen J, Limebeer CL, Parker LA (2009). Potential of the rat model of conditioned gaping to detect nausea produced by rolipram, a phosphodiesterase-4 (PDE4) inhibitor. Pharmacol Biochem Behav 91: 537541.
  • Rutten K, Prickaerts J, Hendrix M, van der Staay FJ, Sik A, Blokland A (2007). Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors. Eur J Pharmacol 558: 107112.
  • Rutten K, Misner DL, Works M, Blokland A, Novak TJ, Santarelli L et al. (2008). Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D) mice. Eur J Neurosci 28: 625632.
  • Rutten K, Van Donkelaar EL, Ferrington L, Blokland A, Bollen E, Steinbusch HW et al. (2009). Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats. Neuropsychopharmacology 34: 19141925.
  • Sik A, van Nieuwehuyzen P, Prickaerts J, Blokland A (2003). Performance of different mouse strains in an object recognition task. Behav Brain Res 147: 4954.
  • Vanmierlo T, Rutten K, Dederen J, Bloks VW, van Vark-van der Zee LC, Kuipers F et al. (2009). Liver X receptor activation restores memory in aged AD mice without reducing amyloid. Neurobiol Aging 32: 12621272.
  • Wang H, Ferguson GD, Pineda VV, Cundiff PE, Storm DR (2004a). Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP. Nat Neurosci 7: 635642.
  • Wang M, Urenjak J, Fedele E, Obrenovitch TP (2004b). Effects of phosphodiesterase inhibition on cortical spreading depression and associated changes in extracellular cyclic GMP. Biochem Pharmacol 67: 16191627.
  • Wielinga PR, van der Heijden I, Reid G, Beijnen JH, Wijnholds J, Borst P (2003). Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. J Biol Chem 278: 1766417671.
  • Wong ST, Athos J, Figueroa XA, Pineda VV, Schaefer ML, Chavkin CC et al. (1999). Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP. Neuron 23: 787798.
  • Zeller E, Stief HJ, Pflug B, Sastre-y-Hernandez M (1984). Results of a phase II study of the antidepressant effect of rolipram. Pharmacopsychiatry 17: 188190.
  • Zhang HT (2009). Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs. Curr Pharm Des 15: 16881698.
  • Zhang HT, Crissman AM, Dorairaj NR, Chandler LJ, O'Donnell JM (2000). Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism. Neuropsychopharmacology 23: 198204.
  • Zhang HT, Huang Y, Jin SC, Frith SA, Suvarna N, Conti N et al. (2002). Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme. Neuropsychopharmacology 27: 587595.
  • Zhang HT, Huang Y, Suvarna NU, Deng C, Crissman AM, Hopper AT et al. (2005). Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats. Psychopharmacology (Berl) 179: 613619.