SEARCH

SEARCH BY CITATION

References

  • Al-Alem L, Bridges PJ, Su W, Gong MC, Iglarz M, Ko C (2007). Endothelin-2 induces oviductal contraction via endothelin receptor subtype A in rats. J Endocrinol 193: 383391.
  • Alexander SPH, Mathie A, Peters JA (2011). Guide to receptors and channels (GRAC), 5th Edition. Br J Pharmacol 164 (Suppl. 1): S1S324.
  • Arinami T, Ishikawa M, Inoue A, Yanagisawa M, Masaki T, Yoshida MC et al. (1991). Chromosomal assignments of the human endothelin family genes: the endothelin-1 gene (EDN1) to 6p23-p24, the endothelin-2 gene (EDN2) to 1p34, and the endothelin-3 gene (EDN3) to 20q13.2-q13.3. Am J Hum Genet 48: 990996.
  • Arvidsson K, Nemoto T, Mitsui Y, Ohashi S, Nakanishi H (1998). The solution structure of human endothelin-2 a 1H-NMR and CD study. Eur J Biochem 257: 380388.
  • Bacon CR, Davenport AP (1996). Endothelin receptors in human coronary artery and aorta. Br J Pharmacol 117: 986992.
  • Bagnato A, Salani D, Di Castro V, Wu-Wong JR, Tecce R, Nicotra MR et al. (1999). Expression of endothelin 1 and endothelin a receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. Cancer Res 59: 720727.
  • Bagnato A, Loizidou M, Pflug BR, Curwen J, Growcott J (2011). Role of the endothelin axis and its antagonists in the treatment of cancer. Br J Pharmacol 163: 220233.
  • Barst RJ, Langleben D, Badesch D, Frost A, Lawrence EC, Shapiro S et al. (2006). Treatment of pulmonary arterial hypertension with the selective endothelin-a receptor antagonist sitaxsentan. J Am Coll Cardiol 47: 20492056.
  • Bayes M, Rabasseda X, Prous JR (2003). Gateways to clinical trials. Methods Find Exp Clin Pharmacol 25: 317340.
  • Belaidi E, Joyeux-Faure M, Ribuot C, Launois SH, Levy P, Godin-Ribuot D (2009). Major role for hypoxia inducible factor-1 and the endothelin system in promoting myocardial infarction and hypertension in an animal model of obstructive sleep apnea. J Am Coll Cardiol 53: 13091317.
  • Bertelsen GA, Rebello S, Gulati A (1992). Characteristics of endothelin receptors in the cerebral cortex and spinal cord of aged rats. Neurobiol Aging 13: 513519.
  • Bhalla A, Haque S, Taylor I, Winslet M, Loizidou M (2009). Endothelin receptor antagonism and cancer. Eur J Clin Invest 39 (Suppl. 2): 7477.
  • Bloch KD, Eddy RL, Shows TB, Quertermous T (1989). cDNA cloning and chromosomal assignment of the gene encoding endothelin 3. J Biol Chem 264: 1815618161.
  • Bloch KD, Hong CC, Eddy RL, Shows TB, Quertermous T (1991). cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2. Genomics 10: 236242.
  • Bohm F, Pernow J, Lindstrom J, Ahlborg G (2003). ETA receptors mediate vasoconstriction, whereas ETB receptors clear endothelin-1 in the splanchnic and renal circulation of healthy men. Clin Sci (Lond) 104: 143151.
  • Borgeson DD, Grantham JA, Williamson EE, Luchner A, Redfield MM, Opgenorth TJ et al. (1998). Chronic oral endothelin type a receptor antagonism in experimental heart failure. Hypertension 31: 766770.
  • Bridges PJ, Jo M, Al-Alem L, Na G, Su W, Gong MC et al. (2010). Production and binding of endothelin-2 (EDN2) in the rat ovary: endothelin receptor subtype A (EDNRA)-mediated contraction. Reprod Fertil Dev 22: 780787.
  • Brown MJ, Sharma P, Stevens PA (2000). Association between diastolic blood pressure and variants of the endothelin-1 and endothelin-2 genes. J Cardiovasc Pharmacol 35: S41S43.
  • Cameron IT, Plumpton C, Champeney R, Van Papendorp C, Ashby MJ, Davenport AP (1993). Identification of endothelin-1, endothelin-2 and endothelin-3 in human endometrium. J Reprod Fertil 98: 251255.
  • Chang I, Bramall A, Baynash AG, Mcinnes RR, Stewart DJ, Yanagisawa M (2009). Genetic study of ET-2 in mice. Eleventh International Conference on Endothelin, 15.
  • Channick RN, Simonneau G, Sitbon O, Robbins IM, Frost A, Tapson VF et al. (2001). Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 358: 11191123.
  • Chao HH, Hong HJ, Liu JC, Lin JW, Chen YL, Chiu WT et al. (2007). Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells. Eur J Pharmacol 573: 4954.
  • Chappell PE, Lydon JP, Conneely OM, O'Malley BW, Levine JE (1997). Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology 138: 41474152.
  • Clapéron A, Rose C, Gane P, Collec E, Bertrand O, Ouimet T (2005). The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. J Biol Chem 280: 2127221283.
  • Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T et al. (1998). Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development 125: 813824.
  • Corder R, Douthwaite JA, Lees DM, Khan NQ, Viseu dos Santos AC, Wood EG et al. (2001). Endothelin-1 synthesis reduced by red wine. Nature 414: 863864.
  • Cozza EN, Chiou S, Gomez-Sanchez CE (1992). Endothelin-1 potentiation of angiotensin II stimulation of aldosterone production. Am J Physiol 262: R85R89.
  • D'Orléans-Juste P, Telemaque S, Claing A (1991). Different pharmacological profiles of big-endothelin-3 and big-endothelin-1 in vivo and in vitro. Br J Pharmacol 104: 440444.
  • D'Orléans-Juste P, Houde M, Rae GA, Bkaily G, Carrier E, Simard E (2008). Endothelin-1 (1-31): from chymase-dependent synthesis to cardiovascular pathologies. Vascul Pharmacol 49: 5162.
  • Davenport AP (2002). International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature. Pharmacol Rev 54: 219226.
  • Davenport AP, Maguire JJ (2006). Endothelin. Handb Exp Pharmacol 176: 295329.
  • Davenport AP, Kuc RE, Maguire JJ, Harland SP (1995). ETA receptors predominate in the human vasculature and mediate constriction. J Cardiovasc Pharmacol 26 (Suppl. 3): S265S267.
  • Davenport AP, Kuc RE, Plumpton C, Mockridge JW, Barker PJ, Huskisson NS (1998). Endothelin-converting enzyme in human tissues. J Mol Histol 30: 359374.
  • Devesly P, Phillips PE, Johns A, Rubanyi G, Parker-Botelho LH (1990). Receptor kinetics differ for endothelin-1 and endothelin-2 binding to Swiss 3T3 fibroblasts. Biochem Biophys Res Commun 172: 126134.
  • Dickstein K, De Voogd HJ, Miric MP, Willenbrock R, Mitrovic V, Pacher R et al. (2004). Effect of single doses of slv306, an inhibitor of both neutral endopeptidase and endothelin-converting enzyme, on pulmonary pressures in congestive heart failure. Am J Cardiol 94: 237239.
  • Douglas SA, Hiley CR (1990). Endothelium-dependent vascular activities of endothelin-like peptides in the isolated superior mesenteric arterial bed of the rat. Br J Pharmacol 101: 8188.
  • Eberle JR, Fecker LF, Orfanos CE, Geilen CC (2002). Endothelin-1 decreases basic apoptotic rates in human melanoma cell lines. J Invest Dermatol 119: 549555.
  • Elferink JG, de Koster BM (1996). The effect of endothelin-2 (ET-2) on migration and changes in cytosolic free calcium of neutrophils. Naunyn Schmiedebergs Arch Pharmacol 353: 130135.
  • Emoto N, Yanagisawa M (1995). Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. J Biol Chem 270: 1526215268.
  • Fecteau MH, Honoré JC, Plante M, Labonté J, Rae GA, Pedro DJ (2005). Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension 46: 8792.
  • Flores JA (2000). Gene expression of endothelin-1 in the porcine ovary: follicular development. Biol Reprod 63: 137713782.
  • Gardiner SM, Compton AM, Bennett T (1990). Regional hemodynamic effects of endothelin-2 and sarafotoxin-S6b in conscious rats. Am J Physiol 258: R912R917.
  • Gardiner SM, Kemp PA, Bennett T (1992). Inhibition by phosphoramidon of the regional haemodynamic effects of proendothelin-2 and -3 in conscious rats. Br J Pharmacol 107: 584590.
  • Giaid A, Gibson SJ, Herrero MT, Gentleman S, Legon S, Yanagisawa M et al. (1991). Topographical localisation of endothelin mRNA and peptide immunoreactivity in neurones of the human brain. Histochemistry 95: 303314.
  • Grant K, Loizidou M, Taylor I (2003). Endothelin-1: a multifunctional molecule in cancer. Br J Cancer 88: 163166.
  • Gratton JP, Rae GA, Bkaily G, D'Orléans-Juste P (2000). ET(B) receptor blockade potentiates the pressor response to big endothelin-1 but not big endothelin-2 in the anesthetized rabbit. Hypertension 35: 726731.
  • Grimshaw MJ, Balkwill FR (2001). Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation – a potential mechanism. Eur J Immunol 31: 480489.
  • Grimshaw MJ, Naylo RS, Balkwill FR (2002a). Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells. Mol Cancer Ther 1: 12731281.
  • Grimshaw MJ, Wilson JL, Balkwill FR (2002b). Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol 32: 23932400.
  • Grimshaw MJ, Hagemann T, Ayhan A, Gillett CE, Binder C, Balkwill FR (2004). A role for endothelin-2 and its receptors in breast tumor cell invasion. Cancer Res 64: 24612468.
  • Guimaraes CL, Calixto JB, Rae GA (1992). Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein. Hypertension 19 (Suppl. 2): S79S86.
  • Hagemann T, Robinson SC, Schulz M, Trümper L, Balkwill FR, Binder C (2004). Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. Carcinogenesis 25: 15431549.
  • Haq A, Kayali M, Hammami MM, Jaroudi K, al-Sedairy ST (1996). Immunoreactive endothelin-1, endothelin-2 and big endothelin-1 in follicular fluids of women undergoing ovulation induction for in-vitro fertilization. Hum Reprod 11: 269273.
  • Harland SP, Kuc RE, Pickard JD, Davenport AP (1995). Characterization of endothelin receptors in human brain cortex, gliomas, and meningiomas. J Cardiovasc Pharmacol 26 (Suppl. 3): S408S411.
  • Harris AL (2002). Hypoxia – a key regulatory factor in tumour growth. Nat Rev Cancer 2: 3847.
  • Haynes WG, Webb DJ (1994). Contribution of endogenous generation of endothelin-1 to basal vascular tone. Lancet 344: 852854.
  • Hickey KA, Rubanyi G, Paul RJ, Highsmith RF (1985). Characterization of a coro- nary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 248: C550C556.
  • Hocher B, Liefeldt L, Thone-Reineke C, Orzechowski HD, Distler A, Bauer C et al. (1996). Characterization of the renal phenotype of transgenic rats expressing the human endothelin-2 gene. Hypertension 28: 196201.
  • Hosoda K, Hammer RE, Richardson JA, Baynash AG, Cheung JC, Giaid A et al. (1994). Targeted and natural (piebald-lethal) mutations of the endothelin-B receptor gene produce megacolon associated with spotted coat color in mice. Cell 79: 12671276.
  • Howard PG, Plumpton C, Davenport AP (1992). Anatomical localization and pharmacological activity of mature endothelins and their precursors in human vascular tissue. J Hypertens 10: 13791386.
  • Inoue A, Yanagisawa M, Kimura S, Kasuva Y, Miyauchi T, Goto K et al. (1989). The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Nat Acad Sci USA 86: 28632867.
  • Ishida N, Tsujioka K, Tomoi M, Saida K, Mitsui Y (1989). Differential activities of two distinct endothelin family peptides on ileum and coronary artery. FEBS Lett 247: 337340.
  • Iwashima A, Kobayashi M, Saida K, Kagamu H, Ohashi S, Arakawa M et al. (1997). Contraction and intracellular calcium-ion elevation of cultured human aortic smooth muscle cells by endothelin-1, vasoactive intestinal contractor (VIC) and the derivatives. In Vitro Cell Dev Biol Anim 33: 751756.
  • Jankovic SM, Jankovic SV, Lukic G, Radonjic V, Cupara S, Stefanovic S (2009). Contractile effects of endothelins on isolated ampullar segment of human oviduct in luteal phase of menstrual cycle. Pharmacol Res 59: 6973.
  • Johnstrom P, Fryer TD, Richards HK, Harris NG, Barret O, Clark JC et al. (2005). Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo. Br J Pharmacol 144: 115122.
  • Kakinuma Y, Miyauchi T, Kobayashi T, Yuki K, Maeda S, Sakai S et al. (1999). Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. Life Sci 65: 16711683.
  • Kalra PR, Moon JC, Coats AJ (2002). Do results of the enable (endothelin antagonist bosentan for lowering cardiac events in heart failure) study spell the end for non-selective endothelin antagonism in heart failure? Int J Cardiol 85: 195197.
  • Karet FE, Davenport AP (1996). Localization of endothelin peptides in human kidney. Kidney Int 49: 382387.
  • Kim J, Bagchi IC, Bagchi MK (2009). Signaling by hypoxia-inducible factors is critical for ovulation in mice. Endocrinology 150: 33923400.
  • Klipper E, Levit A, Mastich Y, Berisha B, Schams D, Meidan R (2010). Induction of endothelin-2 expression by luteinizing hormone and hypoxia: possible role in bovine corpus luteum formation. Endocrinology 151: 19141922.
  • Ko C, Gieske MC, Al-Alem L, Hahn Y, Su W, Gong MC et al. (2006). Endothelin-2 in ovarian follicle rupture. Endocrinology 147: 17701779.
  • Kojima K, Nihei Z (1995). Expression of endothelin-1 immunoreactivity in breast cancer. Surg Oncol 4: 309315.
  • Kurihara H, Kurihara Y, Yazaki Y (2001). Lessons from gene deletion in the endothelin system. Handb Exp Pharmacol 152: 141154.
  • Lambert GL, Barker S, Corder R (1998). Comparison of the regulation of endothelin-2 and endothelin-converting enzyme-1 b [correction of beta] by forskolin and TNF-alpha in ACHN cells. J Cardiovasc Pharmacol 31 (Suppl. 1): S49S51.
  • Lambert GL, Barker S, Lees DM, Corder R (2000). Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression. J Mol Endocrinol 24: 273283.
  • Landan G, Bdolah A, Wollberg Z, Kochva E, Graur D (1991). The evolutionary history of the sarafotoxin/endothelin/endothelin-like superfamily. J Cardiovasc Pharmacol 17 (Suppl. 7): S517S519.
  • Lee ME, Bloch KD, Clifford JA, Quertermous T (1990). Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific cis-acting sequence. J Biol Chem 265: 1044610450.
  • Lee S, Lin M, Mele A, Farmar J, Russo D et al. (1999). Proteolytic processing of big endothelin-3 by the Kell blood group protein. Blood 94: 14401450.
  • Liefeldt L, Rylski B, Walcher F, Manhart J, Kron S, Rosenke YW et al. (2010). Effects of transgenic endothelin-2 overexpression on diabetic cardiomyopathy in rats. Eur J Clin Invest 40: 203210.
  • Lin WW, Lee CY (1992). Intestinal relaxation by endothelin isopeptides: involvement of Ca(2+)-activated K+ channels. Eur J Pharmacol 219: 355360.
  • Lydon JP, Demayo FP, Funk CR, Mani S, Hughes AR, Montgomery CA et al. (1995). Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev 9: 22662278.
  • McCartney SA, Ballinger AB, Vojnovic I, Farthing MJ, Warner TD (2002). Endothelin in human inflammatory bowel disease: comparison to rat trinitrobenzenesulphonic acid-induced colitis. Life Sci 71: 18931904.
  • Maguire JJ, Davenport AP (1995). ETA receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro. Br J Pharmacol 115: 191197.
  • Maguire JJ, Kuc RE, Davenport AP (2001). Vasoconstrictor activity of novel endothelin peptide, ET-1(1-31), in human mammary and coronary arteries in vitro. Br J Pharmacol 134: 13601366.
  • Marciniak SJ, Plumpton C, Barker PJ, Huskisson NS, Davenport AP (1992). Localization of immunoreactive endothelin and proendothelin in the human lung. Pulm Pharmacol 5: 175182.
  • Marone G, DE Crescenzo G, Adt M, Patella V, Arbustini E, Genovese A (1995). Immunological characterization and functional importance of human heart mast cells. Immunopharmacology 31: 118.
  • Masuo Y, Ishikawa Y, Kozakai T, Uchide T, Komatsu Y, Saida K (2003). Vasoactive intestinal contractor/endothelin-2 gene expression in the murine central nervous system. Biochem Biophys Res Commun 300: 661668.
  • Matsumoto H, Suzuki N, Onda H, Fujino M (1989). Abundance of endothelin-3 in rat intestine, pituitary gland and brain. Biochem Biophys Res Commun 164: 7480.
  • Matsumoto H, Suzuki N, Kitada C, Fujino M (1994). Endothelin family peptides in human plasma and urine: their molecular forms and concentrations. Peptides 15: 505510.
  • Mattera GG, Eglezos A, Renzetti AR, Mizrahi J (1993). Comparison of the cardiovascular and neural activity of endothelin-1, -2, -3 and respective proendothelins: effects of phosphoramidon and thiorphan. Br J Pharmacol 110: 331337.
  • Meidan R, Levy N (2007). The ovarian endothelin network: an evolving story. Trends Endocrinol Metab 18: 379385.
  • de la Monte SM, Quertermous T, Hong CC, Bloch KD (1995). Regional and maturation-associated expression of endothelin 2 in rat gastrointestinal tract. J Histochem Cytochem 43: 203209.
  • Morton AJ, Davenport AP (1992). Cerebellar neurons and glia respond differentially to endothelins and sarafotoxin s6b. Brain Res 581: 299306.
  • Na G, Bridges PJ, Koo Y, Ko C (2008). Role of hypoxia in the regulation of periovulatory edn2 expression in the mouse 1. Can J Physiol Pharmacol 2: 310319.
  • Nagai T, Ogimoto A, Okayama H, Ohtsuka T, Shigematsu Y, Hamada M et al. (2007). A985G polymorphism of the endothelin-2 gene and atrial fibrillation in patients with hypertrophic cardiomyopathy. Circ J 71: 19321936.
  • Nakamuta M, Ohashi M, Tabata S, Tanabe Y, Goto K, Naruse M et al. (1993). High plasma concentrations of endothelin-like immunoreactivities in patients with hepatocellular carcinoma. Am J Gastroenterol 88: 248252.
  • Negus RP, Turner L, Burke F, Balkwill FR (1998). Hypoxia down-regulates mcp-1 expression: implications for macrophage distribution in tumors. J Leukoc Biol 63: 758765.
  • O'Reilly G, Charnock-Jones DS, Davenport AP, Cameron IT, Smith SK (1992). Presence of messenger ribonucleic acid for endothelin-1, endothelin-2, and endothelin-3 in human endometrium and a change in the ratio of ETA and ETB receptor subtype across the menstrual cycle. J Clin Endocrinol Metab 75: 15451549.
  • O'Reilly G, Charnock-Jones DS, Cameron IT, Smith SK, Davenport AP (1993a). Endothelin-2 mRNA splice variants detected by RT-PCR in cultured human vascular smooth muscle and endothelial cells. J Cardiovasc Pharmacol 22 (Suppl. 8): S18S21.
  • O'Reilly G, Charnock-Jones DS, Morrison JJ, Cameron IT, Davenport AP, Smith SK (1993b). Alternatively spliced mRNAs for human endothelin-2 and their tissue distribution. Biochem Biophys Res Commun 193: 834840.
  • Ohkubo S, Ogi K, Hosoya M, Matsumoto H, Suzuki N, Kimura C et al. (1990). Specific expression of human endothelin-2 (ET-2) gene in a renal adenocarcinoma cell line. Molecular cloning of cDNA encoding the precursor of ET-2 and its characterization. FEBS Lett 274: 136140.
  • Oliver FJ, de la Rubia G, Feener EP, Lee ME, Loeken MR, Shiba T et al. (1991). Stimulation of endothelin-1 gene expression by insulin in endothelial cells. J Biol Chem 266: 2325123256.
  • Packer M, Mcmurray J, Massie B, Caspi A, Charlon V, Cohensolal A et al. (2005). Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study. J Card Fail 11: 1220.
  • Palanisamy GS, Cheon YP, Kim J, Kannan A, Li Q, Sato M et al. (2006). A novel pathway involving progesterone receptor, endothelin-2, and endothelin receptor B controls ovulation in mice. Mol Endocrinol 20: 27842795.
  • Paulino EC, Steil AA, Jancar S (2006). Effect of endothelins on human neutrophil activation by immune complexes. Int Immunopharmacol 6: 11191125.
  • Plumpton C, Champeney R, Ashby MJ, Kuc RE, Davenport AP (1993). Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated. J Cardiovasc Pharmacol 22 (Suppl. 8): S26S28.
  • Plumpton C, Ashby MJ, Kuc RE, O'Reilly G, Davenport AP (1996). Expression of endothelin peptides and mRNA in the human heart. Clin Sci (Lond) 90: 3746.
  • Poli E, Barboso G, Casoli C, Starcich R, Bertaccini G (1991a). Positive inotropic effect of endothelin-2 on human atrium preparations in vitro. Cardioscience 2: 99104.
  • Poli E, Casoli C, Spaggiari I, Starcich R, Bertaccini G (1991b). Contractile effect of endothelin-2 on the isolated human saphenous vein. Arch Int Pharmacodyn Ther 313: 108119.
  • Rodriguez-Pascual F, Redondo-Horcajo M, Magan-Marchal N, Lagares D, Martinez-Ruiz A, Kleinert H et al. (2008). Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability. Mol Cell Biol 28: 71397155.
  • Roubert P, Gillard V, Plas P, Chabrier PE, Braquet P (1991). Binding characteristics of endothelin isoforms (et-1, ET-2, and et-3) in vascular smooth muscle cells. J Cardiovasc Pharmacol 17 (Suppl. 7): S104S108.
  • Rubin LJ, Badesch DB, Barst RJ, Galie N, Black CM, Keogh A et al. (2002). Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 346: 896903.
  • Saida K, Mitsui Y, Ishida N (1989). A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression, and biological activity. J Biol Chem 264: 1461314616.
  • Saida K, Hashimoto M, Mitsui Y, Ishida N, Uchide T (2000). The prepro vasoactive intestinal contractor (VIC)/endothelin-2 gene (EDN2): structure, evolution, production, and embryonic expression. Genomics 64: 5161.
  • Saida K, Kometani N, Uchide T, Mitsui Y (2002). Sequence analysis and expression of the mouse full-length vasoactive intestinal contractor/endothelin-2 gene (EDN2): comparison with the endothelin-1 gene (EDN1). Clin Sci (Lond) 103 (Suppl. 48): S84S89.
  • Sakai S, Miyauchi T, Kobayashi M, Yamagushi I, Goto K, Sugishita Y (1996). Inhibition of myocardial endothelin pathway improves long-term survival in heart failure. Nature 384: 353355.
  • Schoeffter P, Randriantsoa A (1993). Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur J Pharmacol 249: 199206.
  • Seed A, Kuc RE, Maguire JJ, Hillier C, Johnston F, Essers H, et al. (2012). The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans. Life Sci, doi: 10.1016/j.lfs.2012.03.022.
  • Sharma P, Hingorani A, Jia H, Hopper R, Brown MJ (1999). Quantitative association between a newly identified molecular variant in the endothelin-2 gene and human essential hypertension. J Hypertens 17: 12811287.
  • Shimada K, Takahashi M, Tanzawa K (1994). Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells. J Biol Chem 269: 1827518278.
  • Shirasuna K, Watanabe S, Oki N, Wijayagunawardane MP, Matsui M, Ohtani M et al. (2006). A cooperative action of endothelin-1 with prostaglandin f(2alpha) on luteal function in the cow. Domest Anim Endocrinol 31: 186196.
  • Stow LR, Jacobs ME, Wingo CS, Cain BD (2011). Endothelin-1 gene regulation. FASEB J 25: 1628.
  • Tabrizchi R (2003). Slv-306. Solvay. Curr Opin Investig Drugs 4: 329332.
  • Takai S, Shiota N, Jin D, Miyazaki M (1998). Chymase processes big-endothelin-2 to endothelin-2-(1-31) that induces contractile responses in the isolated monkey trachea. Eur J Pharmacol 358: 229233.
  • Takizawa S, Uchide T, Adur J, Kozakai T, Kotake-Nara E, Quan J et al. (2005). Differential expression of endothelin-2 along the mouse intestinal tract. J Mol Endocrinol 35: 201209.
  • Tanese K, Fukuma M, Ishiko A, Sakamoto M (2010). Endothelin-2 is upregulated in basal cell carcinoma under control of hedgehog signaling pathway. Biochem Biophys Res Commun 391: 486491.
  • Telemaque S, D'Orléans-Juste P (1991). Presence of a phosphoramidon-sensitive endothelin-converting enzyme which converts big-endothelin-1, but not big-endothelin-3, in the rat vas deferens. Naunyn Schmiedebergs Arch Pharmacol 344: 505507.
  • Tokito F, Suzuki N, Hosoya M, Matsumoto H, Ohkubo S, Fujino M (1991). Epidermal growth factor (EGF) decreased endothelin-2 (ET-2) production in human renal adenocarcinoma cells. FEBS Lett 295: 1721.
  • Turner AJ, Murphy LJ (1996). Molecular pharmacology of endothelin converting enzymes. Biochem Pharmacol 51: 91102.
  • Turner L, Scotton C, Negus R, Balkwill F (1999). Hypoxia inhibits macrophage migration. Eur J Immunol 29: 22802287.
  • Uchide T, Masuda H, Mitsui Y, Saida K (1999). Gene expression of vasoactive intestinal contractor/endothelin-2 in ovary, uterus and embryo: comprehensive gene expression profiles of the endothelin ligand-receptor system revealed by semi-quantitative reverse transcription-polymerase chain reaction analysis in adult mouse tissues and during late embryonic development. J Mol Endocrinol 22: 161171.
  • Uchide T, Adur J, Fukamachi T, Saida K (2000). Quantitative analysis of endothelin-1 and vasoactive intestinal contractor/endothelin-2 gene expression in rats by real-time reverse transcriptase polymerase chain reaction. J Cardiovasc Pharmacol 36: S5S8.
  • Vallender TW, Lahn BT (2006). Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. FEBS Lett 580: 45604566.
  • Walles B, Gröschel-Stewart U, Kannisto P, Owman C, Sjöberg NO, Unsicker K (1990). Immunocytochemical demonstration of contractile cells in the human ovarian follicle. Experientia 46: 682683.
  • Watanabe T (1975). Proteolytic activity of mycoplasma salivarium and mycoplasma orale 1. Med Microbiol Immunol 161: 127132.
  • Wright C, Cody W, Dunbar JJ, Doherty A, Hingorani G, Rapundalo S (1994). Characterization of endothelins as chemoattractants for human neutrophils. Life Sci 55: 16331641.
  • Yanagisawa H, Yanagisawa M, Kapur RP, Richardson JA, Williams SC, Clouthier DE et al. (1998). Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development 125: 825836.
  • Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y et al. (1988). A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411415.
  • Yap EY, Battistini B, McKay KO (2000). Contraction to big endothelin-1, big endothelin-2 and big endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi. Br J Pharmacol 129: 170176.
  • Yeligar S, Tsukamoto H, Kalra VK (2009). Ethanol induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxiainducible factor-1alpha and microrNA-199. J Immunol 183: 52325243.
  • Yen H, Zhang Y, Penfold S, Rollins BJ (1997). Mcp-1-mediated chemotaxis requires activation of signal transduction pathways. J Leukoc Biol 61: 529532.
  • Yorimitsu K, Shinmi O, Nishiyama M, Moroi K, Sugita Y, Saito T et al. (1992). Effect of phosphoramidon on big endothelin-2 conversion into endothelin-2 in human renal adenocarcinoma (ACHN) cells. Analysis of endothelin-2 biosynthetic pathway. FEBS Lett 314: 395398.
  • Yorimitsu K, Moroi K, Inagaki N, Saito T, Masuda Y, Masaki T et al. (1995). Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2. Biochem Biophys Res Commun 208: 721727.
  • Yoshinaga M, Chijiiwa Y, Misawa T, Harada N, Nawata H (1992). EndothelinB receptor on guinea pig small intestinal smooth muscle cells. Am J Physiol 262: G308G311.