David R Poyner. David Poyner is a molecular pharmacologist with a long-term interest in GPCRs. While initially working on muscarinic receptors, for the last 20 years he has studied the molecular pharmacology of CGRP.
Secretin family (Class B) G protein-coupled receptors – from molecular to clinical perspectives
Article first published online: 10 APR 2012
© 2012 The Authors. British Journal of Pharmacology © 2012 The British Pharmacological Society
British Journal of Pharmacology
Special Issue: Themed Section: Secretin Family (Class B) G Protein-Coupled Receptors - from Molecular to Clinical Perspectives. Guest Editors: David R Poyner and Debbie L Hay
Volume 166, Issue 1, pages 1–3, May 2012
How to Cite
Poyner, D. R. and Hay, D. L. (2012), Secretin family (Class B) G protein-coupled receptors – from molecular to clinical perspectives. British Journal of Pharmacology, 166: 1–3. doi: 10.1111/j.1476-5381.2011.01810.x
Debbie L Hay. Debbie Hay is a molecular pharmacologist, specialising in structure-function studies of family B GPCRs. In particular, her work focuses on the receptors for the CGRP/adrenomedullin/amylin/calcitonin family of peptides. These receptors are postulated to be good drug targets for a range of conditions including migraine, cardiovascular disease, cancer and diabetes.
- Issue published online: 10 APR 2012
- Article first published online: 10 APR 2012
- Received; 1 December 2011; Accepted; 2 December 2011
- G protein-coupled receptor;
- family B;
Family B G protein-coupled receptors represent an important but under-researched group of receptors. This edition of the British Journal of Pharmacology considers the roles and pharmacology of a number of these receptors. Whilst common themes emerge, it is clear that more work is needed to understand the details of each receptor in order to properly exploit them therapeutically.
LINKED ARTICLES This article is part of a themed section on Secretin Family (Class B) G Protein-Coupled Receptors. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2012.166.issue-1