Liver transplantation in the era of model for end-stage liver disease


Sammy Saab, MD, MPH, Division of Digestive Diseases, 44-138 CHS (MC 168417), UCLA Medical Center, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
Tel: 310-206-6705.
Fax: 310-206-4197.


Abstract: Liver transplantation is challenged by organ shortage and prolonged waiting list time. The goal of the ideal organ allocation system is to transplant individuals least likely to survive without a liver transplantation, and maintain appropriate rates of postoperative survival. Currently, liver allocation in the United States is based on the model for end-stage liver disease (MELD). Studies have shown MELD to be objective and accurate in predicting short-term survival in patients with cirrhosis.