In memoriam of Gianfranco Paci.
Black pigments in the liver related to gold and titanium deposits. a report of four cases
Article first published online: 26 JAN 2007
Volume 27, Issue 3, pages 408–413, April 2007
How to Cite
Brenard, R., Dumortier, P., Del Natale, M., Honhon, B., Van Den Berghe, M., Bataille, C., Rickaert, F., Henrion, J., Peny, M. O. and Rahier, J. (2007), Black pigments in the liver related to gold and titanium deposits. a report of four cases. Liver International, 27: 408–413. doi: 10.1111/j.1478-3231.2006.01431.x
- Issue published online: 26 JAN 2007
- Article first published online: 26 JAN 2007
- Received 19 June 2006accepted 27 November 2006
- black pigments;
- gold deposits;
- titanium deposits
Black pigments are rarely described in the liver. We report four patients with chronic cholestasis and black pigments described on liver histological examination. Energy-dispersive X-ray analysis identified these black pigments as gold particles in the first three patients and titanium particles in the fourth. The origin of the gold deposits was unknown in this first patient and related to gold salts therapy in the two others. Titanium deposits was associated with hepatic granulomas and related to total knee replacement.