Intra-operative ultrasound for detection of liver metastases from colorectal cancer
Version of Record online: 26 OCT 2007
Volume 28, Issue 1, pages 88–94, January 2008
How to Cite
Mazzoni, G., Napoli, A., Mandetta, S., Miccini, M., Cassini, D., Gregori, M., Colace, L. and Tocchi, A. (2008), Intra-operative ultrasound for detection of liver metastases from colorectal cancer. Liver International, 28: 88–94. doi: 10.1111/j.1478-3231.2007.01583.x
- Issue online: 26 OCT 2007
- Version of Record online: 26 OCT 2007
- Received 14 March 2007accepted 14 June 2007
- colorectal cancer;
- intra-operative ultrasound;
- liver metastases
Objective: The aim of this study was to evaluate the accuracy of intra-operative ultrasound (IOUS) imaging in detecting liver secondaries at the time of primary colorectal surgery and to evaluate the impact of IOUS on patient management.
Methods: Data from 167 patients with primary colorectal cancer who were admitted for elective surgery between January 1995 and December 2003 were prospectively evaluated and analysed. All patients underwent pre-operative abdominal ultrasonography (US) and computed tomography (CT), as well as IOUS. The final diagnosis of liver metastases was made by means of histological examination of either biopsy or surgical specimens. The sensitivities of pre-operative US and CT were compared with the sensitivity of IOUS, referred to histology. Changes in surgical management owing to IOUS findings were noted.
Results: IOUS supplied additional information in the case of 31 patients. In 28 of these patients, this information had a major impact on the intra-operative strategy, in that the procedure was altered.
Conclusions: IOUS is safe, simple to perform and more accurate than pre-operative imaging. It reduces the number of patients subjected to superfluous surgery. The use of IOUS is therefore encouraged during colorectal cancer surgery.