Treatment of chronic portosystemic encephalopathy in cirrhotic patients by embolization of portosystemic shunts
Article first published online: 20 NOV 2007
Volume 27, Issue 10, pages 1389–1393, December 2007
How to Cite
Zidi, S. H., Zanditenas, D., Gelu-Siméon, M., Rangheard, A.-S., Valla, D. C., Vilgrain, V. and Pelletier, G. M. (2007), Treatment of chronic portosystemic encephalopathy in cirrhotic patients by embolization of portosystemic shunts. Liver International, 27: 1389–1393. doi: 10.1111/j.1478-3231.2007.01602.x
- Issue published online: 20 NOV 2007
- Article first published online: 20 NOV 2007
- Received 18 May 2007accepted 27 August 2007
- hepatic encephalopathy;
- porta-caval shunt;
- portal embolization;
- portal hypertension
Aims/Backgrounds: Large spontaneous portal-systemic shunts can occasionally be the cause of chronic and disabling encephalopathy in cirrhotic patients. Shunt embolization has been proposed, however the clinical relevance of this technique remains uncertain.
Methods/Results: We report our results in seven patients treated by shunt embolization. Although the procedure was achieved and technically successful in all patients, the clinical results were poor as long-term improvement was obtained in only one patient. Three patients died within 3 months after the procedure from cirrhoses' end stage complications.
Conclusion: We believe that optimal management of these patients with chronic spontaneous encephalopathy is liver transplantation.