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Table S1. Usefulness of serum DCP to screen the patients with HCC. The data indicate sensitivity, specificity, positive predictive value, and negative predictive value as a result of screening for patients with HCC among the patients studied. In all studies indicated, patients with chronic hepatitis and/or cirrhosis were designated as the comparative non-HCC patient group.

Table S2. Usefulness of DCP in serum and/or tissue as a predictive marker of prognosis for patients with HCC. Serum DCP level before curative therapy can be used for the prediction of HCC behavior and this clinical usefulness is effective in various treatment strategies. Furthermore, the clinicopathological significance of tissue DCP expression was clarified although the evidences are not sufficient currently.

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