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Effects of tibolone on the quality of life, anxiety-depression levels and cognitive functions in natural menopause: An observational follow-up study


Correspondence: Dr Leyla Gülseren, 1831 sokak, Centas apt. 50/26, Karsiyaka, Izmir-Turkey. Email:


The effects of tibolone on the quality of life (QoL), depression-anxiety levels and cognitive functions were investigated. Seventeen women received tibolone and 25 women did not receive any medication. At the end of the 6-month follow-up period, the QoL was better in the tibolone group in the area of mental health. Disability, anxiety symptoms, menopausal symptoms were significantly reduced in this group.