Uterine transplantation: one human case followed by a decade of experimental research in animal models


Dr Ash Hanafy, Department of Obstetrics and Gynaecology, Griffith University, 16-30 High Street, Southport, Qld 4215, Australia. Email: a.hanafy@griffith.edu.au


Uterine transplantation (UTx) aims to treat unconditional uterine factor infertility by replacing a non-functioning or non-existing uterus. After one attempt of UTx in the human 10 years ago, intensive research has been performed. The results of these specific studies on surgical technique, ischaemia-reperfusion injury, immunosuppression and fertility are discussed.