A review of the Drosophila (Drosophila) quadrisetata species group is provided on the basis of samples collected from tropical to warm–temperate areas of the Oriental Region and the collection records so far accumulated for all known species. Three new species, D. (D.) aotsukai Suwito & Watabe sp. nov., D. (D.) rinjaniensis Suwito & Watabe sp. nov. and D. (D.) sundaensis Suwito & Watabe sp. nov., are described, and new distribution records and supplementary, revised descriptions are given for known species. A multiple-entry key, based on a character database, to all species of this species group is constructed and uploaded to the Internet.