Periodic stupor-like states in progressive supranuclear palsy
Version of Record online: 3 JUN 2007
Volume 7, Issue 2, pages 87–91, June 2007
How to Cite
SASAYAMA, D., MIYASHITA, M., FUKUDA, T., TAKAHASHI, T., INUZUKA, S., WASHIZUKA, S., HANIHARA, T. and AMANO, N. (2007), Periodic stupor-like states in progressive supranuclear palsy. Psychogeriatrics, 7: 87–91. doi: 10.1111/j.1479-8301.2007.00191.x
- Issue online: 3 JUN 2007
- Version of Record online: 3 JUN 2007
- Received 8 November 2006; accepted 19 December 2006.
- intralaminar thalamic nucleus;
- progressive supranuclear palsy;
- psychiatric symptoms;
- stupor-like state
Four patients with progressive supranuclear palsy presented with various psychiatric symptoms. Periodic stupor-like states due to fluctuations of consciousness were observed in all four cases. Magnetic resonance imaging showed severe dilatation of the third ventricle suggesting atrophy of the thalami. Neuropathological examination in one of the cases confirmed severe fibrillary gliosis in the intralaminar thalamic nucleus. So far, few studies have focused on periodic stupor-like states observed in progressive supranuclear palsy patients. From our cases and from the literature, we postulate that the lesions in the intralaminar thalamic nuclei may have close relevance to the stupor-like states seen in progressive supranuclear palsy patients.