Subjective effects of glycine ingestion before bedtime on sleep quality
Version of Record online: 9 FEB 2006
Sleep and Biological Rhythms
Volume 4, Issue 1, pages 75–77, February 2006
How to Cite
INAGAWA, K., HIRAOKA, T., KOHDA, T., YAMADERA, W. and TAKAHASHI, M. (2006), Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep and Biological Rhythms, 4: 75–77. doi: 10.1111/j.1479-8425.2006.00193.x
- Issue online: 9 FEB 2006
- Version of Record online: 9 FEB 2006
- Accepted for publication 9 August 2005.
- amino acid;
- subjective effect on sleep
The effects of glycine on sleep quality were examined in a randomized double-blinded cross-over trial. The volunteers, with complaints about the quality of their sleep, ingested either glycine (3 g) or placebo before bedtime, and their subjective feeling in the following morning was evaluated with the St. Mary's Hospital Sleep Questionnaire and Space-Aeromedicine Fatigue Checklist. The glycine ingestion significantly improved the following elements: “fatigue”, “liveliness and peppiness”, and “clear-headedness”. These results suggest that glycine produced a good subjective feeling after awakening from sleep.