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Physical Activity as a Protective Factor in Relapse Following Smoking Cessation in Participants with a Depressive Disorder

Authors

  • Paquito Bernard PhD candidate,

    1. Laboratory Epsylon (EA 4556), Dynamics of Human Abilities and Health Behaviors, University of Montpellier, Montpellier, France
    2. Department of Respiratory Medicine, CHU Montpellier, Montpellier, France
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  • Gregory Ninot Pr,

    1. Laboratory Epsylon (EA 4556), Dynamics of Human Abilities and Health Behaviors, University of Montpellier, Montpellier, France
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  • Sebastien Guillaume MD, PhD,

    1. Inserm U1061, Montpellier, France
    2. Department of Psychological Medicine and Psychiatry, CHU Montpellier, Montpellier, France
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  • Guillaume Fond MD,

    1. Inserm U1061, Montpellier, France
    2. Department of Psychological Medicine and Psychiatry, CHU Montpellier, Montpellier, France
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  • Philippe Courtet Pr, MD,

    1. Inserm U1061, Montpellier, France
    2. Department of Psychological Medicine and Psychiatry, CHU Montpellier, Montpellier, France
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  • Marie Christine Picot MDE,

    1. Inserm U1061, Montpellier, France
    2. Epidemiology and Clinical Research Department, CHU Montpellier, Montpellier, France
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  • Xavier Quantin MD

    1. Laboratory Epsylon (EA 4556), Dynamics of Human Abilities and Health Behaviors, University of Montpellier, Montpellier, France
    2. Department of Respiratory Medicine, CHU Montpellier, Montpellier, France
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Dr. Bernard, Laboratory Epsylon EA 4556, Dynamics of Human Abilities and Health Behaviors, University of Montpellier 1, F-34000, France. E-mail: paquito.bernard@univ-montp1.fr.

Abstract

The factors predicting smoking abstinence in depressive smokers, and the role of physical activity in precessation, were investigated. One hundred thirty-three smokers with current major depressive disorders (score ≥10 on the Depression subscale of Hospital Anxiety and Depression Scale) were recruited from a large prospective cohort of smokers (n = 1,119). Over a maximum period of 3 years, regression modeling, adjusted for potential confounders, showed that physical activity was associated with relapse (relapse rate = 0.54, 95% confidence interval = 0.34–0.85, p = .008). Also, antidepressants, anxiolytics, level of education, and number of attempts to quit were associated with relapse. The protective role of physical activity on relapse rate could be a modifiable factor in smoking cessation for smokers with depressive disorders. (Am J Addict 2012;00:1–8)

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