Present address: Department of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
The Helicobacter hepaticus hefA Gene is Involved in Resistance to Amoxicillin
Version of Record online: 15 JAN 2009
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
Volume 14, Issue 1, pages 72–79, February 2009
How to Cite
Belzer, C., Stoof, J., Breijer, S., Kusters, J. G., Kuipers, E. J. and Van Vliet, A. H. M. (2009), The Helicobacter hepaticus hefA Gene is Involved in Resistance to Amoxicillin. Helicobacter, 14: 72–79. doi: 10.1111/j.1523-5378.2009.00661.x
- Issue online: 15 JAN 2009
- Version of Record online: 15 JAN 2009
Alignment of the penicillin-binding protein 1A (PBP-1A) sequence of the amoxicillin-sensitive Helicobacter pylori strain 26695 (indicated by HP0597_AMXS) and of the amoxicillin resistant Hardenberg strain  (indicated by HP0597_AMXR) with that of the amoxicillin-resistant Helicobacter hepaticus strain ATCC 51449 (indicated as HH0890). The alignments was made with the ClustalX2 program , and asterisks represent residues conserved in all sequences, colons represent conserved substitutions, and dots indicate semi-conserved substitutions. The residue listed in yellow background is the Ser414 residue, of which mutation to Arg414 (indicated in green background) has been described to mediate amoxicillin resistance in H. pylori [1,3]. Residues listed in black background are residues which are potentially associated with amoxicillin resistance in H. pylori .
Please note: Wiley-Blackwell are not responsible for the content or functionality of any supporting materials supplied by the authors. Any queries (other than missing material) should be directed to the corresponding author for the article.
|HEL_661_sm_Suppmat.doc||33K||Supporting info item|
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.