Angiolymphoid Hyperplasia with Eosinophilia Associated to a Squamous Cell Carcinoma of the Ear


Address correspondence and reprint requests to: Jorge L. Sánchez, MD, Department of Dermatology, University of Puerto Rico, PO Box 365067, San Juan, Puerto Rico 00936-5067, or e-mail:


Background. Angiolymphoid hyperplasia with eosinophilia is a benign vascular proliferation that usually affects the head and neck region.

Method. An 89-year-old man who had a squamous cell carcinoma on the posterior aspect of one ear developed lesions of angiolymphoid hyperplasia with eosinophilia on the anterior aspect of the same ear.

Results. After surgical treatment of the malignant neoplasm, the lesions of angiolymphoid hyperplasia with eosinophilia disappeared spontaneously.

Conclusions. Damage to the vasculature of the ear by the malignant neoplasm or the release of angiogenic factors by the same neoplasm is a plausible explanation for the development and eventual resolution of the vascular proliferation