Treatment of Infraorbital Dark Circles Using a Low-Fluence Q-Switched 1,064-nm Laser
Article first published online: 23 MAY 2011
© 2011 by the American Society for Dermatologic Surgery, Inc.
Volume 37, Issue 6, pages 797–803, June 2011
How to Cite
XU, T.-H., YANG, Z.-H., LI, Y.-H., CHEN, J. Z., GUO, S., WU, Y., LIU, W., GAO, X.-H., HE, C.-D., GENG, L., XIAO, T. and CHEN, H.-D. (2011), Treatment of Infraorbital Dark Circles Using a Low-Fluence Q-Switched 1,064-nm Laser. Dermatologic Surgery, 37: 797–803. doi: 10.1111/j.1524-4725.2011.01956..x
- Issue published online: 23 MAY 2011
- Article first published online: 23 MAY 2011
OBJECTIVE To evaluate the efficacy and safety of the low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminium garnet (QSNY) laser in treating infraorbital dark circles.
PARTICIPANTS AND METHODS Thirty women with infraorbital dark circles (predominant color dark brown) participated in this open-label study. Participants underwent eight sessions of low-fluence QSNY laser treatment at 4.2 J/cm2 at 3- to 4-day intervals. A spot size of 3.5 mm was used, with a pulse duration of 8 ns. The melanin deposition in the lesional skin was observed in vivo using reflectance confocal microscopy (RCM). Morphologic changes were evaluated using a global evaluation, an overall self-assessment, a narrow-band reflectance spectrophotometer, and a skin hydration measurement instrument.
RESULTS Twenty-six of 30 patients showed global improvement that they rated as excellent or good. Twenty-eight rated their overall satisfaction as excellent or good. The melanin index indicated a substantial decrease, from 225.84 at baseline to 182.65 (p<.05). RCM results showed a dramatic decrease of melanin deposition in the upper dermis. Adverse effects were minimal.
CONCLUSIONS The characteristic finding for dark-brown infraorbital dark circles is melanin deposition in the upper dermis. Treatment of infraorbital dark circles using low-fluence 1,064-nm QSNY laser is safe and effective.
The authors have indicated no significant interest with commercial supporters.