Get access

A Retrospective Study of Q-Switched Alexandrite Laser in Treating Nevus of Ota

Authors


  • Equal first author: Jia Liu and Yuan-Ping Ma

Address correspondence and reprint requests to: Yuan-Hong Li, MD & PhD, Department of Dermatology, No.1 Hospital of China Medical University, 155N. Nanjing Street, Shenyang 110001, PR China, or e-mail: liyuanhong@vip.sina.com. Co-correspondence to: Hong-Duo Chen, MD, Department of Dermatology, No.1 Hospital of China Medical University, 155N. Nanjing Street, Shenyang 110001 P.R.China, or e-mail: hongduochen@hotmail.com.

Abstract

BACKGROUND The Q-switched alexandrite laser (QSAL) has been clinically proven to be effective in treating nevus of Ota, but a large-scale retrospective study with long-term follow-up has never been performed.

OBJECTIVE To evaluate the efficacy of the QSAL in treating nevus of Ota, the laser's long-term side effects, complications associated with the treatments, and the recurrence rate.

MATERIALS AND METHODS Eight hundred six patients (651 female, 155 male) with a diagnosis of nevus of Ota who had received a series of QSAL (wavelength 755 nm) treatments were recruited. The typical settings were fluences of 3.8 to 4.8 J/cm2 and a spot size of 3 mm. Follow-ups were conducted via questionnaire with 590 patients who had completed the treatment at least 3 years earlier.

RESULTS Overall, 93.9% of patients achieved complete clearance after an average of 5.2 sessions. All recurrences (0.8%) appeared beyond the previously treated sites. No long-term adverse effects, including hypopigmentation, hyperpigmentation, textural changes, and malignant transformation, were observed.

CONCLUSION The QSAL is a safe and effective modality for treating nevus of Ota. Recurrence was rare and appeared beyond the previously treated sites.

The authors have indicated no significant interest with commercial supporters.

Get access to the full text of this article

Ancillary