The Impact of Health Literacy on Health-Related Quality of Life (HRQoL) and Utility Assessment among Patients with Rheumatic Diseases
Article first published online: 6 NOV 2009
© 2009, International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
Value in Health
Special Issue: Pharmacoeconomics and Outcomes Research in Asia
Volume 12, Issue Supplement s3, pages S106–S109, November/December 2009
How to Cite
Zhang, X.-H., Li, S.-C., Fong, K.-Y. and Thumboo, J. (2009), The Impact of Health Literacy on Health-Related Quality of Life (HRQoL) and Utility Assessment among Patients with Rheumatic Diseases. Value in Health, 12: S106–S109. doi: 10.1111/j.1524-4733.2009.00640.x
- Issue published online: 6 NOV 2009
- Article first published online: 6 NOV 2009
- health literacy;
- health utility;
- rheumatic disease
Objectives: The objective of this study was to investigate the impact of health literacy (HL) on health-related quality of life (HRQoL) and utility assessment among patients with rheumatic diseases.
Methods: HL was measured by the rapid estimate of adult literacy in medicine (REALM) and was characterized as low or adequate. HRQoL and utility scores were assessed using the SF-36, SF-6D, and EQ-5D. Comparisons of sociodemographics and HRQoL in patients with low or adequate HL were made using t test, chi-square, or Mann–Whitney U tests. Spearman's correlation and partial correlations were used to study the relationship between HL, HRQoL, and utility scores, with significant correlations further explored using multiple linear regression models.
Results: Data were analyzed from 199 subjects. Patients with adequate HL had significantly higher education levels, better dwelling status, lower disease activity, and better physical functioning (PF). There was a significant although weak correlation between HL level and PF. After adjustment, HL level was shown to independently explain 3.7% of the variance in the PF score. Nevertheless, there was no impact of HL on utility assessment or other HRQoL domains.
Conclusion: HL did not impact HRQoL in general, but was found to have a weak impact on the PF of patients with rheumatic diseases.