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Editorials: The Cardiovascular Effects of Arteriovenous Fistulas in Chronic Kidney Disease: A Cause for Concern?


Address correspondence to: Jennifer MacRae, Division of Nephrology, Foothills Medical Center, 1403 29th St. NW, Calgary, AB, T2N 2T9, Canada, or e-mail:


Arteriovenous fistulas (AVFs) are the preferred type of vascular access, but relatively little is known regarding their effects on cardiovascular remodeling and cardiac function. The following is a review regarding the immediate and long-term complications associated with AVF creation, including the development of left ventricular hypertrophy, high-output cardiac failure, exacerbation of coronary ischemia, and the possible contribution to the development of central vein stenosis.