1Present address: Université Pierre et Marie Curie, Bât. A, 5ème etage, case 29, 7 Quai Saint Bernard, 75005 Paris, France
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Variation in fiber number of a male-specific muscle between Drosophila species: a genetic and developmental analysis
Article first published online: 20 JUL 2007
DOI: 10.1111/j.1525-142X.2007.00174.x
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How to Cite
Orgogozo, V., Muro, N. M. and Stern, D. L. (2007), Variation in fiber number of a male-specific muscle between Drosophila species: a genetic and developmental analysis. Evolution & Development, 9: 368–377. doi: 10.1111/j.1525-142X.2007.00174.x
Publication History
- Issue published online: 20 JUL 2007
- Article first published online: 20 JUL 2007
Corrected by:
Vol. 9, Issue 5, 520, Article first published online: 6 SEP 2007
- Abstract
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SUMMARY We characterize a newly discovered morphological difference between species of the Drosophila melanogaster subgroup. The muscle of Lawrence (MOL) contains about four to five fibers in D. melanogaster and Drosophila simulans and six to seven fibers in Drosophila mauritiana and Drosophila sechellia. The same number of nuclei per fiber is present in these species but their total number of MOL nuclei differs. This suggests that the number of muscle precursor cells has changed during evolution. Our comparison of MOL development indicates that the species difference appears during metamorphosis. We mapped the quantitative trait loci responsible for the change in muscle fiber number between D. sechellia and D. simulans to two genomic regions on chromosome 2. Our data eliminate the possibility of evolving mutations in the fruitless gene and suggest that a change in the twist might be partly responsible for this evolutionary change.