MicroRNA-183 family conservation and ciliated neurosensory organ expression
Version of Record online: 3 JAN 2008
Evolution & Development
Volume 10, Issue 1, pages 106–113, January/February 2008
How to Cite
Pierce, M. L., Weston, M. D., Fritzsch, B., Gabel, H. W., Ruvkun, G. and Soukup, G. A. (2008), MicroRNA-183 family conservation and ciliated neurosensory organ expression. Evolution & Development, 10: 106–113. doi: 10.1111/j.1525-142X.2007.00217.x
- Issue online: 3 JAN 2008
- Version of Record online: 3 JAN 2008
Fig. S1. miR-183 family members and homologs identified in the sea squirt genome (cin) and purple sea urchin genome (spu). Shown are predicted miRNA precursor hairpin structures with homologous miRNA sequences reported in Fig. 1B highlighted in red. Genomic scaffold segments corresponding to depicted sequences are indicated. The highlighted position in the terminal loop of the precursor hairpin for spu-miR-183-like (blue) denotes the site of G to U transversion in the sequence determined for green sea urchin (sdr).
Fig. S2. Discrimination by probes for miR-183 and spu-miR-183-like. (A) ISH detecting expression of miR-183 in acorn worm compared to probe for spu-miR-183-like and negative control lacking probe. Scale bars indicate 100 μm. (B) ISH detecting expression of miR-183 in mouse cochlea compared to probe for spu-miR-183-like. miR-183 expression is specifically detected in the single row of inner hair cells (IHC) and three rows of outer hair cells (OHC). Scale bars indicate 20μm.
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