Leiomyosarcoma of the broad ligament: a case report and review of literature


Address correspondence and reprint requests to: Domenico Amoroso, MD, Department of Medical Oncology B, National Institute for Cancer Research, P.le R. Benzi 10, 16132 Genova, Italy. Email: amos59@tiscali.it


Abstract.  Murialdo R, Usset A, Guido T, Carli F, Boccardo F, Amoroso D. Leiomyosarcoma of the broad ligament: a case report and review of literature. Int J Gynecol Cancer 2005;15:1226–1229

Leiomyosarcoma of the broad ligament is a rare tumor, since only 12 cases have been reported so far in the literature. A 53-year-old patient was diagnosed with leiomyosarcoma of the broad ligament at the Department of Gynecology Oncology of the National Cancer Research Institute in Genoa. The tumor had low mitotic activity and less than ten mitotic figures were found for ten high-power fields. The treatment consisted of total abdominal hysterectomy and bilateral salpingo-oophorectomy with bilateral ureteral neoanastomosis and omentectomy. The patient has not received either radiotherapy or chemotherapy, considering the low grade of malignancy, but she is only followed up on an outpatient basis. No evidence of metastasis has been noted after a follow-up of 13 months. It is concluded that low-grade leiomyosarcoma of the broad ligament should be treated only with surgery.