Multimodal therapy for the initial management of genital embryonal rhabdomyosarcoma in childhood

Authors

  • N.R. MAHARAJ,

    Corresponding author
    1. Departments of *Obstetrics and Gynaecology and †Paediatric Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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  • D. NIMAKO,

    1. Departments of *Obstetrics and Gynaecology and †Paediatric Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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  • G.P. HADLEY

    1. Departments of *Obstetrics and Gynaecology and †Paediatric Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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Niren Ray Maharaj, FCOG(SA), MMed(O&G), Department of Obstetrics and Gynaecology, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Private Bag 7, Congella, Durban 4013, South Africa. Email: maharajn13@ukzn.ac.za

Abstract

Rhabdomyosarcoma is the most common soft tissue sarcoma found in children. A polypoid form of the embryonal type of rhabdomyosarcoma, namely, sarcoma botryoides, is often found in girls younger than 5 years, and typically presents as a polypoid mass protruding from the vagina. Over the years, there has been a shift in the treatment of this condition from radical surgery to a multimodal approach involving conservative surgery with chemotherapy and radiotherapy. This approach has been associated with improved survival and preservation of normal anatomy and function. We discuss the initial management of a 4-year-old girl with pelvic embryonal rhabdomyosarcoma using a multimodal approach.

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