Abstract We assessed the beliefs of 49 college students regarding the acquired immunodoficiency syndrome (AIDS), condom use, and sexual behaviors related to AIDS prevention. Roy's modes of self-concept, interdependence, and role function were used as a framework to find psychosocial determinants that influence safer sex practices. Interdependence was measured by a sexual regard scale. Beliefs regarding both AIDS beliefs and condom were very positive. Students were selectively using safer sex practices; most reported avoiding high-risk partners, but only 39% were using condoms. No significant associations were found among the four independent measures of AIDS beliefs, condom beliefs, self-esteem, and sexual regard or with the dependent measure. AIDS safer sex practices. A two-hour safer sex educational module did change several beliefs but did not increase safer sex practices. Most participating students stated they had a good understanding of how AIDS was spread, they knew how to use condoms correctly, and they discussed AIDS with friends and parents.