Etiologic Factors in Diaper Dermatitis: The Role of Feces
Version of Record online: 20 MAR 2008
Volume 3, Issue 2, pages 107–112, February 1986
How to Cite
Buckingham, K. W. and Berg, R. W. (1986), Etiologic Factors in Diaper Dermatitis: The Role of Feces. Pediatric Dermatology, 3: 107–112. doi: 10.1111/j.1525-1470.1986.tb00499.x
- Issue online: 20 MAR 2008
- Version of Record online: 20 MAR 2008
Abstract: While the etiology of diaper dermatitis in infants is complex, it is generally believed to involve an interaction between skin and irritants in feces and urine. Proteases and lipases were identified as the major irritants in the feces of infants, and bile salts were found to potentiate the damage produced by the action of fecal enzymes on skin. Fecal enzymes also increased the permeability of skin, thereby increasing potential susceptibility to other irritants in the diaper environment.