Sweet Syndrome as the Presenting Manifestation of Chronic Granulomatous Disease in an Infant


Address correspondence to Ph. Labrune, M.D., Service de Pédiatrie, Hôpital Antoine Bèclére, 157 rue de la Porte de Trivaux, 92141 Clamart Cedex, France.


Abstract: A 2.5-month-old infant had Sweet syndrome. Chronic granulomatous disease was subsequently diagnosed by the nitroblue tetrazolium reduction test. To date, this infant is the youngest reported with Sweet syndrome. Moreover, the association of chronic granulomatous disease with this syndrome has not been previously described. The precise relationship between the conditions remains to be determined. Granulocyte function should be evaluated in any infant with Sweet syndrome.