Plaque-like Myofibroblastic Tumor of Infancy


Address correspondence to Jennie T. Clarke, M.D., Department of Dermatology HU-14, Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, or e-mail:


Abstract:  Fibrohistiocytic neoplasms are relatively uncommon in infancy and childhood. We report an unusual spindle cell tumor occurring in two infants within the first 3 months of life. These tumors histologically resembled dermatofibromas, but the young age of onset, large size, and plaque-like morphology were distinctly different from those of dermatofibromas. The features of these neoplasms are discussed and the differential of other spindle cell tumors of infancy is reviewed.