Multiple Lichenoid Juvenile Xanthogranuloma


Address correspondence to Antonio Torrelo, M.D., Department of Dermatology, Hospital del Nino Jesus, Manandez Pelayo 65, Madrid 28009, Spain, or e-mail:


Abstract:  A 2-year-old boy had hundreds of discrete, small, flat yellow to brown colored papules distributed over the face, neck, and trunk. Biopsy revealed a well-demarcated infiltrate within the papillary dermis composed of histiocytes and some Touton giant cells and eosinophils. The cells were negative for protein S-100 and CD1a but positive for CD68 staining. No systemic lesions of juvenile xanthogranuloma were identified. Lichenoid juvenile xanthogranuloma is a very infrequent variant of juvenile xanthogranuloma.