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Sweet Syndrome in Infancy


Address correspondence to Melinda R. Mohr, M.D., Department of Dermatology, Eastern Virginia Medical School, 700 West Olney Road, Norfolk, VA 23507, or e-mail:


Abstract:  Sweet syndrome, or acute febrile neutrophilic dermatosis, is characterized by the presence of fever, peripheral leukocytosis, painful erythematous plaques and nodules, and a predominately neutrophilic dermal infiltrate. We report a case occurring in a 10-week-old male child, with preceding upper respiratory tract, and gastrointestinal infection symptoms. Sweet syndrome occurring in an infant should prompt a work-up for immunodeficiency, as well as a review of the peripheral blood smear to rule out the rare case of malignancy.