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Recalcitrant Palmoplantar Pustular Psoriasis Treated with Etanercept


Address correspondence to Uxua Floristan Muruzabal, M.D., La Paz University Hospital, Paseo Castellana 261, Madrid 28046, Spain, or e-mail:


Abstract:  We report a 10-year-old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children.