S100-Negative Indeterminate Cell Histiocytosis in an African American Child Responsive to Narrowband Ultraviolet B
Article first published online: 15 SEP 2011
© 2011 Wiley Periodicals, Inc.
Volume 28, Issue 5, pages 524–527, September/October 2011
How to Cite
Bard, S., Torchia, D., Connelly, E. A., Duarte, A. M., Badiavas, E. V. and Schachner, L. A. (2011), S100-Negative Indeterminate Cell Histiocytosis in an African American Child Responsive to Narrowband Ultraviolet B. Pediatric Dermatology, 28: 524–527. doi: 10.1111/j.1525-1470.2011.01305.x
- Issue published online: 15 SEP 2011
- Article first published online: 15 SEP 2011
Abstract: Indeterminate cell histiocytosis is a rare cutaneous disease characterized by the presence of dendritic cells that lack Birbeck granules and immunophenotypically shares features of both Langerhans cells and macrophages. We describe a case of a 4-year-old African American boy affected by a disseminated, exclusively mucocutaneous form of indeterminate cell histiocytosis. The eruption was successfully treated with narrowband ultraviolet B. The peculiar negativity of the Langerhans cell marker S100 is also discussed.