Linear Immunoglobulin A Bullous Disease of Childhood Responsive to Intravenous Immunoglobulin Monotherapy


Address correspondence to Arti Nanda, M.D., DNBE, PO Box: 6759, Salmiya 22078, Salmiya, Kuwait, or e-mail:


Abstract:  We report a case of linear immunoglobulin A bullous disease in a 9-year-old boy who presented with rapidly progressive severe disease and could not tolerate dapsone because of high liver enzymes within a week after a low dose of dapsone in association with an underlying fatty liver. He showed remarkable improvement with intravenous immunoglobulins used as monotherapy, with a rapid clearance and a sustained remission after stopping the treatment.